Results 101 to 110 of about 8,287,486 (375)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
Special Issue “Computational Social Science”
Information, 2019 The last centuries have seen a great surge in our understanding and control of “simple” physical, chemical, and biological processes through data analysis and the mathematical modeling of their underlying dynamics [...]
Gerardo Iñiguez +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
CICT: New Eyes on Computational Competence in Computational Science
ITM Web of Conferences, 2018 Science does not exists to enlighten people's minds only. It mainly exists to show the educated way from quanta to qualia. And that way starts from computational competence. In previous papers published elsewhere, we have already shown that traditional Q
Fiorini Rodolfo A.
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MANIFESTO OF COMPUTATIONAL SOCIAL SCIENCE
Mediações: Revista de Ciências Sociais, 2013 The increasing integration of technology into our lives has created unprecedented volumes of data on society’s everyday behaviour. Such data opens up exciting new opportunities to work towards a quantitative understanding of our complex social systems ...
Rosaria Conte +13 more
doaj +1 more source
Quantum Mechanics with Trajectories: Quantum Trajectories and Adaptive Grids [PDF]
, 2003 Although the foundations of the hydrodynamical formulation of quantum mechanics were laid over 50 years ago, it has only been within the past few years that viable computational implementations have been developed.
Bittner, Eric R., Wyatt, Robert E.
core +2 more sources
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
GREENER principles for environmentally sustainable computational science
Nature Computational Science, 2023 Loïc Lannelongue +9 more
semanticscholar +1 more source
Visualization in Computational Science
Procedia Computer Science, 2010 AbstractThis section and the papers that follow relate to to the workshop on Visualization in Computational Science which is held at the Tenth International Conference on Computational Science (ICCS2010) in Amsterdam, the Netherlands. This workshop brings together experts from visualization research and end-users to illustrate the state of the art and ...
openaire +3 more sources