Results 111 to 120 of about 8,550,305 (373)
Ubiquity symposium: The science in computer science: unplugging computer science to find the science [PDF]
Ubiquity, 2014 The Computer Science Unplugged project provides activities that enable students to engage with concepts from computer science without having to program. Many of the activities provide the basis of a scientific exploration of computer science, and thus help students to see the relationship of the discipline with science.
openaire +2 more sources
FEBS Open Bio, EarlyView.Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti +8 more
wiley +1 more source
Generative AI has lowered the barriers to computational social sciences [PDF]
, 2023 Yongjun Zhang
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Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
International Journal of Communication, 2019 This article reviews the opportunities and challenges for computational research methods in the field of communication. Among the social sciences, communication stands out as a discipline with a relatively low-profile institutionalized focus on the in ...
Martin Hilbert +15 more
doaj +2 more sources
Computational sense: the role of technology in the education of digital librarians [PDF]
, 2006 The rapid progress of digital library technology from research to implementation has created a force for change in the curricula of library schools. The education of future librarians has always had to adapt to new technologies but the pace, complexity ...
Nichols, David M., Twidale, Michael B.
core +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Forecasting high-impact research topics via machine learning on evolving knowledge graphs
Machine Learning: Science and TechnologyThe exponential growth in scientific publications poses a severe challenge for human researchers. It forces attention to more narrow sub-fields, which makes it challenging to discover new impactful research ideas and collaborations outside one’s own ...
Xuemei Gu, Mario Krenn
doaj +1 more source