Results 111 to 120 of about 8,980,708 (398)

MANIFESTO OF COMPUTATIONAL SOCIAL SCIENCE

Mediações: Revista de Ciências Sociais, 2013
The increasing integration of technology into our lives has created unprecedented volumes of data on society’s everyday behaviour. Such data opens up exciting new opportunities to work towards a quantitative understanding of our complex social systems ...
Rosaria Conte, Nigel Gilbert, Giullia Bonelli, Claudio Cioffi-Revilla, Guillaume Deffuant, János Kertész, Vittorio Loreto, Suzy Moat, Jean-Pierre Nadal, Ángel Sánchez, Andrzej Nowak, Andreas Flache, Maxi San Miguel, Dirk Helbing   +13 more
doaj   +1 more source

FAIR and Open Computer Science Research Software [PDF]

arXiv, 2019
In computational science and in computer science, research software is a central asset for research. Computational science is the application of computer science and software engineering principles to solving scientific problems, whereas computer science is the study of computer hardware and software design. The Open Science agenda holds that science
arxiv  

GREENER principles for environmentally sustainable computational science

Nature Computational Science, 2023
Loïc Lannelongue, Hans-Erik G. Aronson, A. Bateman, E. Birney, Talia Caplan, M. Juckes, J. Mcentyre, Andrew D. Morris, Gerry Reilly, Michael J Inouye   +9 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Nmag micromagnetic simulation tool - software engineering lessons learned

, 2016
We review design and development decisions and their impact for the open source code Nmag from a software engineering in computational science point of view. We summarise lessons learned and recommendations for future computational science projects.
Albert, Maximilian, Fangohr, Hans, Franchin, Matteo   +2 more
core   +1 more source

Forecasting high-impact research topics via machine learning on evolving knowledge graphs

Machine Learning: Science and Technology
The exponential growth in scientific publications poses a severe challenge for human researchers. It forces attention to more narrow sub-fields, which makes it challenging to discover new impactful research ideas and collaborations outside one’s own ...
Xuemei Gu, Mario Krenn
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Interdisciplinarity through internationality: Results from a US–Mexico graduate course bridging computational and plant science

Plant Direct
Interdisciplinarity is used to integrate and synthesize new research directions between scientific domains, but it is not the only means by which to generate novelty by bringing diverse perspectives together.
Daniel H. Chitwood, Alejandra Rougon‐Cardoso, Robert VanBuren   +2 more
doaj   +1 more source

Mechanistic models in computational social science

Frontiers in Physics, 2015
Quantitative social science is not only about regression analysis or, in general, data inference. Computer simulations of social mechanisms have an over 60 years long history. They have been used for many different purposes—to test scenarios, to test the
Petter eHolme, Fredrik eLiljeros
doaj   +1 more source