Results 121 to 130 of about 8,980,708 (398)
Logic Column 18: Alternative Logics: A Book Review [PDF]
This article discusses two books on the topic of alternative logics in science: "Deviant Logic", by Susan Haack, and "Alternative Logics: Do Sciences Need Them?", edited by Paul Weingartner.
arxiv
Visualization in Computational Science
AbstractThis section and the papers that follow relate to to the workshop on Visualization in Computational Science which is held at the Tenth International Conference on Computational Science (ICCS2010) in Amsterdam, the Netherlands. This workshop brings together experts from visualization research and end-users to illustrate the state of the art and ...
openaire +3 more sources
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Quantum Mechanics with Trajectories: Quantum Trajectories and Adaptive Grids [PDF]
Although the foundations of the hydrodynamical formulation of quantum mechanics were laid over 50 years ago, it has only been within the past few years that viable computational implementations have been developed.
Bittner, Eric R., Wyatt, Robert E.
core +2 more sources
Computational reproducibility in computational social science
Open science practices have been widely discussed and have been implemented with varying success in different disciplines. We argue that computational-x disciplines such as computational social science, are also susceptible to the symptoms of the crises,
David Schoch+3 more
doaj +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Computer science is a social science.
Computer science can, and never will be the same again.
openaire +2 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal+3 more
wiley +1 more source
Computational Thinking Integration into Middle Grades Science Classrooms: Strategies for Meeting the Challenges [PDF]
This paper reports findings from the efforts of a university-based research team as they worked with middle school educators within formal school structures to infuse computer science principles and computational thinking practices.
Akram, Bita+7 more
core +1 more source