Results 131 to 140 of about 8,287,486 (375)

BioModels—15 years of sharing computational models in life science

open access: yesNucleic Acids Res., 2019
Computational modelling has become increasingly common in life science research. To provide a platform to support universal sharing, easy accessibility and model reproducibility, BioModels (https://www.ebi.ac.uk/biomodels/), a repository for mathematical
Rahuman S. Malik-Sheriff   +23 more
semanticscholar   +1 more source

A Meta-Theory of Boundary Detection Benchmarks [PDF]

open access: yes, 2012
Human labeled datasets, along with their corresponding evaluation algorithms, play an important role in boundary detection. We here present a psychophysical experiment that addresses the reliability of such benchmarks. To find better remedies to evaluate
Hou, Xiaodi   +2 more
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Computational materials science

open access: yesMoldavian Journal of the Physical Sciences, 2014
First-principles simulation, meaning density-functional theory calculations with plane waves and pseudopotentials, has become a prized technique in condensed-matter theory.
Nazarov, Mihail, Arellano, I.
doaj  

Maps of Computer Science

open access: yes2014 IEEE Pacific Visualization Symposium, 2014
10 pages, 8 figures, live version and source code available at mocs.cs.arizona ...
Stephen G. Kobourov, Daniel Fried
openaire   +3 more sources

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Protein Design is NP-hard [PDF]

open access: yes, 2002
Biologists working in the area of computational protein design have never doubted the seriousness of the algorithmic challenges that face them in attempting in silico sequence selection. It turns out that in the language of the computer science community,
Pierce, Niles A., Winfree, Erik
core  

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

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