Results 291 to 300 of about 3,211,994 (375)

Computational study on the mechanism of small molecules inhibiting NLRP3 with ensemble docking and molecular dynamic simulations. [PDF]

BMC Pharmacol Toxicol
Qin P, Niu Y, Duan J, Lin P.
europepmc   +1 more source

Key attributes of health and environmental risk decision‐making: A scoping review

Risk Analysis, EarlyView.
Abstract Government agencies, international institutions, and independent experts have published approaches for the assessment and management of health and environmental risks. This includes evidence‐based strategies and publications supporting risk decision‐making frameworks reflecting contemporary practices, the overarching context, and governance ...
Yadvinder Bhuller, Xaand Bancroft, Raywat Deonandan, Agnes Grudniewicz, Anne Wiles, Daniel Krewski   +5 more
wiley   +1 more source

Absorption of Toxicants from the Ocular Surface: Potential Applications in Toxicology. [PDF]

Biomedicines
Šoša I, Perković M, Baniček Šoša I, Grubešić P, Linšak DT, Strenja I.   +5 more
europepmc   +1 more source

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

The Journal of Physiology, EarlyView.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai, Xijin Xu, Xia Huo, Joost H. N. Schuitemaker, Marijke M. Faas   +4 more
wiley   +1 more source

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

Frontiers in Toxicology
Kan Shao, Kan Shao, Chao Ji, Bernard Gadagbui   +3 more
doaj   +1 more source

The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk. [PDF]

Hum Genomics
Messier KP, Reif DM, Marvel SW.
europepmc   +1 more source

Bayesian gene set benchmark dose estimation for "omic" responses. [PDF]

Bioinformatics
Zilber D, Messier KP, House J, Parham F, Auerbach SS, Wheeler MW.   +5 more
europepmc   +1 more source

Ameliorative role of naringenin in MPTP- induced Parkinsonism: Insights from <i>Drosophila melanogaster</i> experimental model combined with computational biology. [PDF]

Toxicol Rep
Okonta C, Ogunyemi OM, Olabuntu B, Abolaji AO.   +3 more
europepmc   +1 more source

Association of phthalate exposure with type 2 diabetes and the mediating effect of oxidative stress: A case-control and computational toxicology study

Yuxuan Tan, Ziang Guo, Huojie Yao, Han Liu, Yingyin Fu, Yangxu Luo, Rong He, Yiwan Liu, Pei Li, Lihong Nie, Lei Tan, Chunxia Jing   +11 more
openalex   +1 more source

Detection of Body Packs in Abdominal CT scans Through Artificial Intelligence; Developing a Machine Learning-based Model. [PDF]

Arch Acad Emerg Med
Hosseini SM, Mohtarami SA, Shadnia S, Rahimi M, Erfan Talab Evini P, Mostafazadeh B, Memarian A, Heidarli E.   +7 more
europepmc   +1 more source