Results 241 to 250 of about 613,456 (310)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Comparison of Dimensional Accuracy and Stability of 3D-Printed, Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM), and Conventional Polymethyl Methacrylate (PMMA) Denture Base Materials: An In Vitro Study. [PDF]

Cureus
Borse P, Jain S, Bhasin N, Grover RK, Singh B, Longkumer P.   +5 more
europepmc   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Evaluation of marginal accuracy of polyetheretherketone and zirconia copings fabricated using computer-aided design/computer-aided manufacturing technique: An in vitro study. [PDF]

J Indian Prosthodont Soc
Jangade M, Sharma R, Sudharson NA, Jain R, Sahu SK, Dani A.   +5 more
europepmc   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Computer-Aided Design and Biological Evaluation of Diazaspirocyclic D₄R Antagonists. [PDF]

ACS Chem Neurosci
Jones CAH, Brown BP, Schultz DC, Engers J, Kramlinger VM, Meiler J, Lindsley CW.   +6 more
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Economic renovation of a hillside drip irrigation system using drip tape inlet pressure regulators under computer-aided design. [PDF]

Sci Rep
Wang X, Zhang C, Li G.
europepmc   +1 more source

An in vitro evaluation of tensile strength of molar endocrown milled from various computer aided design and manufacturing materials. [PDF]

Sci Rep
Taha AI, Saad AE.
europepmc   +1 more source

In Vitro Assessment of Linear Dimensional Accuracy of Polyvinyl Siloxane-Based Computer-Aided Design and Transparent Interocclusal Record Materials at 3 Different Storage Times. [PDF]

Med Sci Monit
Alamri M, Sayed ME, Al-Makramani BMA, Gangadharappa P, Al Moaleem MM, AlResayes SS, Hassan NN, Almarzouki M, Daish MA, Yankisar FA, Hasousah SQ, Alqahtani AT, Alfaifi MA, Ayoub M, Mattoo K.   +14 more
europepmc   +1 more source