Results 101 to 110 of about 424,101 (310)
Time for a New Class of Methods and Computer Aided Tools to Address the Challenges Facing Us?
Chemical Engineering Transactions, 2018 This paper highlights the need for a new class of computer aided tools applicable for a wide range of chemicals-based product synthesis-design and the sustainable design of their corresponding manufacturing processes. The new tools are needed to meet the
Anjan K Tula +2 more
doaj +1 more source
Computer-aided modeling for efficient and innovative product-process engineering [PDF]
, 2011 Model baserede computer understøttet produkt process engineering har opnået øget betydning i forskelligste industrielle brancher som for eksampel farmaceutisk produktion, petrokemi, finkemikalier, polymerer, bioteknologi, fødevarer, energi og vand. Denne
Heitzig, Martina
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Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Dual modality prompt learning for visual question-grounded answering in robotic surgery
Visual Computing for Industry, Biomedicine, and ArtWith recent advancements in robotic surgery, notable strides have been made in visual question answering (VQA). Existing VQA systems typically generate textual answers to questions but fail to indicate the location of the relevant content within the ...
Yue Zhang +5 more
doaj +1 more source
Computer labs on virtual environments: A flexible, portable and multidisciplinary model [PDF]
, 2016 Teaching of computer-aided practical subjects in engineering education creates new challenges. Computers have to be configured to support particular requirements of each subject. Virtual Environments allows the building of a Virtual Machine (VM) tailored
Ariza Gómez, María Teresa +4 more
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Applied SciencesHigh-entropy alloys (HEAs) possess multi-element composition and uniform structure, exhibiting superior microstructure and properties compared to traditional alloys. However, the multi-element composition of HEAs results in a complex internal composition
Shen-Yung Lin, Bo-Chun Chen
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
NASA Tech Briefs, August 2000 [PDF]
Topics include: Simulation/Virtual Reality; Test and Measurement; Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation ...
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source