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Computer Aided Engineering of Cyber-Physical Information Gathering and Utilizing Systems [PDF]
Journal of Systemics, Cybernetics and Informatics, 2012 Engineering Cyber-physical information gathering and utilizing systems(CIGUS) presents the systems engineer with a difficult, multi-criterion, multi-objective decision problem.
Alfred P. Defonzo, Anthony P. Hopf
doaj
Large space antennas: A systems analysis case history [PDF]
The value of systems analysis and engineering is aptly demonstrated by the work on Large Space Antennas (LSA) by the NASA Langley Spacecraft Analysis Branch.
Keafer, Lloyd S., Lovelace, U. M.
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Object oriented fault diagnosis system for space shuttle main engine redlines [PDF]
A great deal of attention has recently been given to Artificial Intelligence research in the area of computer aided diagnostics. Due to the dynamic and complex nature of space shuttle red-line parameters, a research effort is under way to develop a real ...
Mohapatra, Saroj Kumar, Rogers, John S.
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Computer Aided Design and Analysis in Die/Mould of Casting Process [PDF]
, 1997 Computer Aided Design (CAD) and Computer Aided Analysis (CAA) have been investigated and developed since the last twenty years as standalone systems.
Abedin, Md. Shamsul
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Computer graphics application in the engineering design integration system [PDF]
The computer graphics aspect of the Engineering Design Integration (EDIN) system and its application to design problems were discussed. Three basic types of computer graphics may be used with the EDIN system for the evaluation of aerospace vehicles ...
Abel, R. W. +5 more
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KUE-online - a data-management-system supporting the handling of design exercises [PDF]
, 2000 This contribution shows a way to introduce topics like CAD (Computer Aided Design) and EDM/PDM (Engineering/Product Data Management) into the lecture courses within the framework of the studies of Production Engineering at the Saarland University in ...
Muth, Michael, Weber, Christian
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Stiffness and Lightweight Enhancement in Biomimetic Design of a Grinding Machine-Tool Structure
Applied SciencesAs global manufacturing faces rising energy costs, environmental pressures, and machining precision, the development trends of the machine tools are moving towards lightweight and high-rigidity structures.
Shen-Yung Lin, Yen-Ting Lai
doaj +1 more source