Results 131 to 140 of about 602,785 (287)

Computer geometry: Rep-tiles with a hole

, 2018
A cube is an 8-rep-tile: it is the union of eight smaller copies of itself. Is there a set with a hole which has this property? The computer found an interesting and complicated solution, which then could be simplified.
Bandt, Christoph, Mekhontsev, Dmitry
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Measuring coherence of computer-assisted likelihood ratio methods

, 2015
Rudolf Haraksim, Daniel Ramos, Didier Meuwly, Charles E.H. Berger   +3 more
openalex   +2 more sources

The Computer-Assisted Web Interview Method as Used in the National Study of ICT Use in Primary Healthcare in Poland – Reflections on a Case Study [PDF]

, 2015
Paweł Sowa, Bartosz Pędziński, Michalina Krzyżak, Dominik Maślach, Sylwia E. Wojcik, Andrzej Szpak   +5 more
openalex   +1 more source

Computer-assisted robotic system for autonomous unicompartmental knee arthroplasty

, 2023
Omar Shalash, Philip Rowe
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Recognition of the lumbar spine using MRI plane-based FiLM conditioning and patient dependent batching on semantic segmentation

Current Directions in Biomedical Engineering
Lower back pain (LBP) is a common symptom that can be linked to the degeneration of intervertebral discs or injuries to vertebrae. Accurate segmentation of lumbar spinal structures is vital for image-based surgery planning but can be resource intensive ...
Stelzner Tim, Baur David, Neumann Juliane, Berger Johann, Völker Anna, Heyde Christoph-E., Neumuth Thomas, Bieck Richard   +7 more
doaj   +1 more source

Operationalizing Mobile Computer-assisted TB Screening and Diagnosis With Wellness on Wheels (WoW)) in Nigeria: Balancing Feasibility and Iterative Efficiency [PDF]

, 2020
Rupert Eneogu, Ellen M.H. Mitchell, Chidubem Ogbudebe, Danjuma Aboki, Victor Anyebe, Chimezie B. Dimkpa, Daniel Egbule, Bassey Nsa, Emmy van der Grinten, Festus Soyinka, Hussein Abdur-Razzaq, Sani Useni, Adebola Lawanson, Simeon Onyemaechi, Emperor Ubochioma, Jerod Scholten, Johan Verhoef, Peter Nwadike, Chukwueme Nkem, Mustapha Gidado, Debby Nongo   +20 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Generating rate equations for complex enzyme systems by a computer-assisted systematic method [PDF]

, 2009
Feng Qi, Ranjan K. Dash, Yu Han, Daniel Beard   +3 more
openalex   +1 more source