Results 131 to 140 of about 2,559,571 (361)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Advances in Computer Assisted Learning Selected Proceedings from the CAL 85 Symposium

open access: yes, 1986
Advances in Computer Assisted Learning contains selected proceedings from the CAL Symposium on Computer Assisted Learning held at the University of Nottingham in the UK in 1985.
Smith, P. R.
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Computer-assisted assessment application using EPM.

open access: yes, 2018
Computer-assisted assessment application using EPM.
Hikmat Ullah Khan (800885)   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Computer-assisted planning and patient-specific instruments for bone tumor surgery within the pelvis – an experimental study

open access: yes, 2013
Resecting bone tumors within the pelvis is challenging due to the complex geometry, limited visibility and restricted workspace of the pelvic bone. Tumor resection requires good cutting accuracy to achieve satisfactory margins and avoid the risk of local
Banse, Xavier   +6 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Context-specific computer-assisted language learning: research, development and practice

open access: yes, 2019
This book presents the findings and outcomes of recent work in the field of computer-assisted language learning (CALL) and offers opportunities for readers to engage in meaningful discussions on the use of technology for language learning and teaching in

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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Computer-assisted language learning: learners, teachers and tools

open access: yes, 2014
This book is an examination of contemporary issues related to learners, teachers and tools in computer-assisted language learning (CALL) environments.

core  

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