Results 191 to 200 of about 576,672 (286)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Glossary of Computer-Assisted Implant Surgery and Related Terms. First Edition. [PDF]

Clin Exp Dent Res
Jorba-Garcia A, Pozzi A, Chen Z, Chow J, Doliveux R, Leung YY, Maruo K, Pimkhaokham A, Sadilina S, Siu A, Vietor K, Wang F, Wu Y, Yi M, Al-Nawas B, Mattheos N, ITI Network on CAIS.   +16 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Computer-assisted cognitive remediation (CACR) as a recovery-oriented intervention for schizophrenia: a randomized controlled trial. [PDF]

BMC Psychiatry
Fathi Azar E, Oftadeh Balani S, Motevalli S, Mirzaie H, Haghgoo HA.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Effects of the computer-assisted rehabilitation environment on patient rehabilitation: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Liang Z, Huang Q, He D, Wang J, Peng R, Zhang J, Xiao X.   +6 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Computer-Assisted Implant Surgery: Patients' Experience and Perspectives. [PDF]

Clin Exp Dent Res
Yeo XH, Uei LJ, Yi M, Kungsadalpipob K, Subbalehka K, Al-Nawas B, Mattheos N.   +6 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Computer-Assisted Implant Surgery: Implications for Teaching, Learning, and Educational Strategies. [PDF]

Clin Exp Dent Res
Uei LJ, Yeo XH, Leung YY, Pelekos G, Nawas BA, Mattheos N.   +5 more
europepmc   +1 more source