Results 41 to 50 of about 575,957 (284)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Computer assisted self and peer assessment: applications, challenges and opportunities [PDF]
, 2010 This paper discusses self and peer assessment (SPA) using CASPAR (Computer Assisted Self and Peer Assessment Ratings) – a software tool designed to aid the administration of SPA.
Lugosi, Peter
core +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Computer assisted mathematical programming [PDF]
, 1987 A Computer Assisted Mathematical Programming (Modelling) System (CAMPS) is described in this paper. The system uses program generator techniques for model creation and contrasts with earlier approaches which use a special purpose language to construct ...
Lucas, CA, Mitra, G
core
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Stability and sensitivity of Learning Analytics based prediction models [PDF]
, 2015 Learning analytics seek to enhance the learning processes through systematic measurements of learning related data and to provide informative feedback to learners and educators.
Giesbers, B. +2 more
core +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
12th GAMM - IMACS International Symposium on Scientific Computing, Computer Arithmetic and Validated Numerics (SCAN 2006), 2006 This paper discusses the problem what makes a computer-assisted proof trustworthy, the quest for an al- gorithmic support system for computer-assisted proof, re- lations to global optimization, an analysis of some recent proofs, and some current challenges which appear to be amenable to a computer-assisted treatment.
openaire +3 more sources