Results 51 to 60 of about 4,605,719 (377)
Computer-Assisted Retrosynthesis Based on Molecular Similarity
ACS Central Science, 2017 We demonstrate molecular similarity to be a surprisingly effective metric for proposing and ranking one-step retrosynthetic disconnections based on analogy to precedent reactions.
Connor W. Coley +3 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Heidelberg colorectal data set for surgical data science in the sensor operating room
Scientific Data, 2021 Measurement(s) colorectum Technology Type(s) Laparoscopy Factor Type(s) surgery type Sample Characteristic - Organism Homo sapiens Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare ...
Lena Maier-Hein +34 more
doaj +1 more source
Homotopy hyperbolic 3-manifolds are hyperbolic [PDF]
, 2003 This paper introduces a rigorous computer-assisted procedure for analyzing hyperbolic 3-manifolds. This procedure is used to complete the proof of several long-standing rigidity conjectures in 3-manifold theory as well as to provide a new lower bound for
Gabai, David +2 more
core +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
End-to-End Deep Learning CT Image Reconstruction for Metal Artifact Reduction
Applied Sciences, 2021 Metal artifacts are common in CT-guided interventions due to the presence of metallic instruments. These artifacts often obscure clinically relevant structures, which can complicate the intervention.
Dominik F. Bauer +5 more
doaj +1 more source
The Effect of Using Computer Technology Tools to Enhance the Teaching-Learning Process in CAD-CAM-CNC Module in Mechanical Engineering Subject Area [PDF]
, 2010 This study presents the evaluation of Computer Assisted Learning (CAL) package included in the teaching and learning methodology of computer aided design- computer aided design - computer numerical control (CAD-CAM-CNC) module.
Abdulrasool, Salah Mahdi +3 more
core
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Current Directions in Biomedical Engineering, 2021 We introduce a system that allows the immediate identification and inspection of fat and muscle structures around the lumbar spine as a means of orthopaedic diagnostics before surgical treatment.
Bieck Richard +7 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source