Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Diagnosis of Multiple-Voltage Design with Bridge Defect
Multiple voltage is an effective dynamic power reduction design technique commonly used in low-power ICs. To the best of our knowledge, there is no reported work for diagnosing multiple-voltage enabled ICs, and the aim of this paper is to propose a ...
Reddy, Sudhakar M. +3 more
core
Clinical Validation of Plasma p‐217tau in Neurological Diseases
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
A New Approach for Effective Retrieval of Medical Images: A Step towards Computer-Assisted Diagnosis. [PDF]
Sharma S, Aggarwal A.
europepmc +1 more source
Computer-assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults. [PDF]
Ferrante di Ruffano L +17 more
europepmc +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Ralph Joseph Ligueran +3 more
doaj +1 more source
Dynamic Hyper-Graph Inference Framework for Computer-Assisted Diagnosis of Neurodegenerative Diseases. [PDF]
Zhu Y +5 more
europepmc +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Computer-Assisted Diagnosis System for Breast Cancer in Computed Tomography Laser Mammography (CTLM). [PDF]
Jalalian A +5 more
europepmc +1 more source

