Results 121 to 130 of about 17,096,706 (238)

The Generalised Image Fusion Toolkit (GIFT)

, 2006
Image fusion provides a mechanism to combine multiple images into a single representation to aid human visual perception and image processing tasks. Such algorithms endeavour to create a fused image containing the salient information from each source ...
Mueller, Daniel, Maeder, Anthony, O'Shea, Peter   +2 more
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Application of deep learning reconstruction in abdominal magnetic resonance cholangiopancreatography for image quality improvement and acquisition time reduction

Journal of the Formosan Medical Association
Purpose: To compare deep learning (DL)-based and conventional reconstruction through subjective and objective analysis and ascertain whether DL-based reconstruction improves the quality and acquisition speed of clinical abdominal magnetic resonance ...
Po-Ting Chen, Chen-Ya Yeh, Yu-Chien Chang, Pohua Chen, Chia-Wei Lee, Charng-Chyi Shieh, Chien-Yuan Lin, Kao-Lang Liu   +7 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Intelligent systems for computer-assisted clinical endoscopic image analysis

, 2004
The importance of computer-assisted diagnosis in endoscopy is to assist the physician in detecting the status of tissues by characterising the features from the endoscopic image.
Boulougoura, M., Kodogiannis, V., Wadge, E., Chowdrey, H.S.   +3 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics

Insights into Imaging
Objectives Achieving a consensus on a definition for different aspects of radiomics workflows to support their translation into clinical usage. Furthermore, to assess the perspective of experts on important challenges for a successful clinical workflow ...
Ralf Floca, Jonas Bohn, Christian Haux, Benedikt Wiestler, Frank G. Zöllner, Annika Reinke, Jakob Weiß, Marco Nolden, Steffen Albert, Thorsten Persigehl, Tobias Norajitra, Bettina Baeßler, Marc Dewey, Rickmer Braren, Martin Büchert, Eva Maria Fallenberg, Norbert Galldiks, Annika Gerken, Michael Götz, Horst K. Hahn, Johannes Haubold, Tobias Haueise, Nils Große Hokamp, Michael Ingrisch, Andra-Iza Iuga, Marco Janoschke, Matthias Jung, Lena Sophie Kiefer, Philipp Lohmann, Jürgen Machann, Jan Hendrik Moltz, Johanna Nattenmüller, Tobias Nonnenmacher, Benedict Oerther, Ahmed E. Othman, Felix Peisen, Fritz Schick, Lale Umutlu, Barbara D. Wichtmann, Wenzhao Zhao, Svenja Caspers, Heinz-Peter Schlemmer, Christopher L. Schlett, Klaus Maier-Hein, Fabian Bamberg   +44 more
doaj   +1 more source