Results 61 to 70 of about 538,674 (304)

Hierarchical Salient Object Detection for Assisted Grasping

, 2017
Visual scene decomposition into semantic entities is one of the major challenges when creating a reliable object grasping system. Recently, we introduced a bottom-up hierarchical clustering approach which is able to segment objects and parts in a scene ...
Cremers, Armin Bernd, Gaspers, Bastian, Illing, Boris, Klein, Dominik Alexander, Schulz, Dirk   +4 more
core   +1 more source

Accelerating root system phenotyping of seedlings through a computer-assisted processing pipeline

Plant Methods, 2017
There are numerous systems and techniques to measure the growth of plant roots. However, phenotyping large numbers of plant roots for breeding and genetic analyses remains challenging.
L. Dupuy, G. Wright, Jacqueline A. Thompson, Anna Taylor, Sebastien Dekeyser, Christopher P. White, W. Thomas, M. Nightingale, J. Hammond, N. Graham, Catherine L. Thomas, M. Broadley, P. White   +12 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Laypersons’ perception of smile esthetics from different backgrounds

Dental Research Journal
Background: Smile esthetics can be subjective. This study aims to assess the effect of culture/geographic location on judging smile esthetics by comparing the perception of smile characteristics between American laypersons (Western culture) and Iranians (
Fereshteh Najarzadegan, Faezeh Eslamipour   +1 more
doaj   +1 more source

Morphometric analysis of neurons from the marginal and substantia gelatinosa layers of human spinal cord: Classification according to laminar organization [PDF]

Vojnosanitetski Pregled, 2005
The main goal of morphometric analysis of neuronal images, except for getting information about their geometry and dendritic branching patterns, is their classification based on laminar organization.
Milošević Nebojša T., Ristanović Dušan S., Stanković Jovan B., Nedeljkov Vladimir B.   +3 more
doaj   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

AI-based CT assessment of 3117 vertebrae reveals significant sex-specific vertebral height differences

Scientific Reports
Predicting vertebral height is complex due to individual factors. AI-based medical imaging analysis offers new opportunities for vertebral assessment. Thereby, these novel methods may contribute to sex-adapted nomograms and vertebral height prediction ...
Viktoria Palm, Subasini Thangamani, Bettina Katalin Budai, Stephan Skornitzke, Kira Eckl, Elizabeth Tong, Sam Sedaghat, Claus Peter Heußel, Oyunbileg von Stackelberg, Sandy Engelhardt, Taisiya Kopytova, Tobias Norajitra, Klaus H. Maier-Hein, Hans-Ulrich Kauczor, Mark Oliver Wielpütz   +14 more
doaj   +1 more source

Introduction to the Special Issue on Computer-Assisted Imaging Processing and Machine Learning Applications on Diagnosis of Chest Radiograph [PDF]

, 2022
Shuihua Wang‎, Zheng Zhang, Yuankai Huo   +2 more
openalex   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source