Results 141 to 150 of about 465,123 (372)

Diagnostic Challenge in Frontal Variant Alzheimer's Disease With Low Amyloid‐β PET Retention

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diagnosing frontal variant Alzheimer's disease (fvAD) is difficult and could be even more difficult when amyloid‐beta (Aβ) PET retention is low. A 63‐year‐old woman presenting with a 3‐year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral frontotemporal atrophy on MRI.
Ryosuke Shimasaki   +5 more
wiley   +1 more source

Technology’s edge: the educational benefits of computer-aided instruction [PDF]

open access: yes
Because a significant portion of U.S. students lacks critical mathematic skills, schools across the country are investing heavily in computerized curriculums as a way to enhance education output, even though there is surprisingly little evidence that ...
Cecilia Elena Rouse   +2 more
core  

The design and application of a decision-making process for identification of critical curricular variables which affect optimal application of CAI in a baccalaureate school of nursing [PDF]

open access: yes, 2020
Ph.D. University of Kansas, Curriculum and Instruction 1981There is a need for a model which will guide nursing educators in making decisions about the critical curricular variables involved in the implementation of computer-assisted instruction ...
Edison, Carolyn Collier
core  

Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Valosin‐containing protein (VCP)‐associated multisystem proteinopathy 1 (MSP1) is caused by variants in the VCP gene. MSP1 results in various phenotypes including progressive myopathy, Paget's disease of bone, frontotemporal dementia, amyotrophic lateral sclerosis, and parkinsonism, among others.
Lindsay N. Alfano   +15 more
wiley   +1 more source

The effect of computer-assisted instruction in improving mathematics performance of low-achieving ninth-grade students [PDF]

open access: yes, 1991
The purpose of this study was to determine whether computer assisted instruction of mathematics produces significantly greater improvement in mathematics performance of low achieving ninth grade students than teaching mathematics skills without computer ...
Bailey, Thomas Everett
core   +1 more source

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden   +15 more
wiley   +1 more source

PENGEMBANGAN MEDIA COMPUTER ASSISTED INSTRUCTION PADA MATA PELAJARAN KIMIA MATERI STOIKIOMETRI BAGI SISWA KELAS X SMA TERBUKA DI SMA NEGERI 19 SURABAYA [PDF]

open access: yes, 2015
Pendidikan dalam pelaksanaannya selama ini masih kurang dapat dijangkau oleh semua orang baik itu dalam segi ruang dan waktu utamanya pada jenjang SMA.
ANDRIAN S, PANJI
core   +1 more source

Nuclei‐Specific Amygdala Enlargement Is Linked to Psychiatric Comorbidities in Drug‐Resistant Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre   +15 more
wiley   +1 more source

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