Results 121 to 130 of about 12,884 (200)

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Computer-Assisted Intraoperative Navigation in Pediatric Head and Neck Surgical Oncology: A Single-Center Case Series and Scoping Review of the Literature. [PDF]

Cancers (Basel)
Whittles J, Bharathan A, Hall S, Baumgartner J, Lopez J.   +4 more
europepmc   +1 more source

A Label‐Free Hyperspectral Imaging Device for Ex Vivo Characterization and Grading of Meningioma Tissues

Journal of Biophotonics, EarlyView.
HyperProbe1.1 enables rapid, label‐free biochemical mapping of freshly resected meningiomas. By quantifying endogenous biomarkers such as cytochrome c oxidase, hemoglobin derivatives, and lipids, the system reveals molecular signatures consistent with tumor grading and generates spatial maps that visualize metabolic and vascular heterogeneity across ...
Pietro Ricci, Camilla Bonaudo, Ivan Ezhov, Anam Toaha, Dorotea Nardini, Manuel Camelia, Federica Lucidi, Filippo Nozzoli, Tim Mach, Ilias Tachtsidis, Daniel Rueckert, Alessandro Della Puppa, Luca Giannoni, Francesco S. Pavone   +13 more
wiley   +1 more source

AI in Radiation Oncology: A Comprehensive Review of Current Applications and Future Directions. [PDF]

Cureus
Zafar F, Vilsan J, Mani S, Al Yousif AR, Cano-Reyes SE, Abraham G, de Barros Neto JF, Imam B, Aluko M, Sikdar S.   +9 more
europepmc   +1 more source

Evaluating Brief Behavioural Activation for depression in adolescents with acquired brain injury using a single‐case experimental design

JCPP Advances, EarlyView.
Abstract Background Adolescents who have had an acquired brain injury (ABI) commonly experience depression. Brief Behavioural Activation (Brief BA) is a successful, values‐based intervention for managing depression in neurotypical adolescents. This study investigated the effectiveness of Brief BA, using a single‐case experimental design, with ...
Conor R. O’Brien, Jenny Limond, Shirley Reynolds, Laura Pass, Anna‐Lynne R. Adlam   +4 more
wiley   +1 more source

Clinical application of cone beam CT in intensity-modulated radiotherapy for the moderate to severe thyroid-associated ophthalmopathy. [PDF]

J Appl Clin Med Phys
Kang D, Hu H, Ma S, Bin S.
europepmc   +1 more source

Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT MRI of the heart and abdominal organs provides unparalleled soft tissue contrast and quantitative biomarkers, yet remains highly susceptible to physiological motion. Contractions of the myocardium, respiratory excursions, peristalsis, vascular pulsatility, and unpredictable bulk patient movement generate artifacts that impair image quality ...
Eric M. Schrauben, Gastao Lima da Cruz, Christopher W. Roy, Thomas Küstner   +3 more
wiley   +1 more source

Reducing low-dose exposure in helical TomoTherapy for locally advanced left-sided breast cancer with a deformable image registration-based dose-mimicking workflow. [PDF]

J Appl Clin Med Phys
Chang CC, Tsai JT, Hsu SM.
europepmc   +1 more source

Healing Beams: Radiation and Radiotherapy in Novels, Poems, Music, Film, Painting

Journal of Medical Radiation Sciences, EarlyView.
Radiation and radiotherapy are perceived by patients and the general public as mysterious, dangerous and healing. The image of radiation and radiotherapy can be analysed by studying novels, poems, music, film and painting. Our paper reviews how radiation and radiotherapy are perceived by patients, the general public, as reflected in various art genres.
Ad A. Kaptein, Jan W. Schoones, Yvette M. van der Linden, Brian M. Hughes   +3 more
wiley   +1 more source

Use of CAD/CAM Workflow and Patient-Specific Implants for Maxillary Reconstruction: A Systematic Review. [PDF]

J Clin Med
D'Alpaos D, Badiali G, Ceccariglia F, Nosrati A, Tarsitano A.   +4 more
europepmc   +1 more source