Results 141 to 150 of about 7,258,714 (254)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Annealing Based Optimization Methods for Signal Processing Applications

open access: yes, 2003
In this thesis, a class of combinatorial optimization methods rooted in statistical mechanics and their use in signal processing applications will be discussed. The thesis consists of two separate parts.
Persson, Per
core  

Computer Assisted Survey Information Collection

open access: yes
The Subcommittee on Computer Assisted Survey Information Collection investigated the use of computers in collecting survey information. This report covers the different ways in which small computers can be used to improve data collection.
United States. Federal Committee on Statistical Methodology. Subcommittee on Computer Assisted Survey Information Collection
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Nonlinear formant-pitch prediction using recurrent neural networks

open access: yes, 2015
8th European Signal Processing Conference, EUSIPCO 1996 -- 1996-09-10 through 1996-09-13 -- Trieste -- 115734In this study, a parallel structure is proposed for the nonlinear formant and pitch prediction of speech signals using Recurrent Neural Networks (
Hacio?lu, Kadri, Varo?lu, Ekrem
core  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

A Reproducible MRI-Based Pipeline for Longitudinal Tracking of Laser-Assisted Bioprinted Cells in Three-Dimensional Constructs. [PDF]

open access: yesNMR Biomed
Medojević M   +7 more
europepmc   +1 more source

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