Results 221 to 230 of about 885,099 (311)

The Application of Artificial Intelligence in Spine Surgery: A Scoping Review. [PDF]

open access: yesJ Am Acad Orthop Surg Glob Res Rev
Shi L, Wang H, Shea GK.
europepmc   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

open access: yesFEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti   +5 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

68-channel neural signal processing system-on-chip with integrated feature extraction, compression, and hardware accelerators for neuroprosthetics in 22 nm FDSOI. [PDF]

open access: yesFront Neurosci
Guo L   +15 more
europepmc   +1 more source

Routine machine quality assurance tests for a self‐shielded gyroscopic radiosurgery system

open access: yesJournal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Purpose This report describes routine machine quality assurance (QA) (daily, monthly, and annual QA) tests for the Zap‐X® Gyroscopic Radiosurgery® platform. Methods Following the recommendations of the American Association of Physicists in Medicine Task Group (AAPM TG)‐142 and Medical Physics Practice guideline (MPPG) 8.b, routine machine QA ...
Yongsook C. Lee   +6 more
wiley   +1 more source

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