Results 51 to 60 of about 285,213 (243)

Computer aided vertebral visualization and analysis: a methodology using the sand rat, a small animal model of disc degeneration

BMC Musculoskeletal Disorders, 2003
Background The purpose of this study is to present an automated system that analyzes digitized x-ray images of small animal spines identifying the effects of disc degeneration.
Hanley Edward N, Najarian Kayvan, Brown Darien, Wilson Christy, Gruber Helen E   +4 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Modulation-mode and power-assignment for SVD-and GMD-assisted downlink MIMO systems [PDF]

, 2010
Multiuser multiple-input multiple-output (MIMO) downlink (DL) transmission schemes experience both multiuser interference (MUI) as well as inter-antenna interference.
Ahrens, Andreas, Aust, Sebastian, Benavente Peces, César   +2 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

An Open CAPT System for Prosody Practice: Practical Steps towards Multilingual Setup

Languages
This paper discusses the challenges posed in creating a Computer-Assisted Pronunciation Training (CAPT) environment for multiple languages. By selecting one language from each of three different language families, we show that a single environment may be
John Blake, Natalia Bogach, Akemi Kusakari, Iurii Lezhenin, Veronica Khaustova, Son Luu Xuan, Van Nhi Nguyen, Nam Ba Pham, Roman Svechnikov, Andrey Ostapchuk, Dmitrei Efimov, Evgeny Pyshkin   +11 more
doaj   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Semi-blind adaptive beamforming for high-throughput quadrature amplitude modulation systems

, 2010
A semi-blind adaptive beamforming scheme is proposed for wireless systems that employ high-throughput quadrature amplitude modulation signalling. A minimum number of training symbols, equal to the number of receiver antenna arrays elements, are first ...
Chen, Sheng, Hanzo, Lajos, Yao, Wang
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Wavelet Features for Recognition of First Episode of Schizophrenia from MRI Brain Images [PDF]

, 2014
Machine learning methods are increasingly used in various fields of medicine, contributing to early diagnosis and better quality of care. These outputs are particularly desirable in case of neuropsychiatric disorders, such as schizophrenia, due to the ...
Dluhos, P., Kasparek, T., Schwarz, D.
core   +1 more source