Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Artificial Empathy in Therapy and Healthcare: Advancements in Interpersonal Interaction Technologies. [PDF]
Cyborg Bionic SystJia T +5 more
europepmc +1 more source
Warfarin Guide: Co-Design of a Mobile Computer-Assisted Anticoagulant Therapy
, 2017 Martin Gerdes +4 more
openalex +2 more sources
Simplified Evaluation and Documentation of Data from Glucose Controlled Insulin Systems (GCIIS) [PDF]
, 1984 Göhl, M. +4 more
core +1 more source
Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang +16 more
wiley +1 more source
Computer-assisted cognitive-behavioral therapy for adolescent depression in primary care clinics in Santiago, Chile (YPSA-M): study protocol for a randomized controlled trial [PDF]
, 2014 Vania Martínez +4 more
openalex +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Calvarial Resurfacing for the Surgical Management of Ossified Cephalohematoma Using Computer-assisted Planning and 3 Dimensional-printed Guides. [PDF]
Plast Reconstr Surg Glob OpenBlount T, Whittles J, Lopez J.
europepmc +1 more source
Computer assisted optimization of cardiac resynchronization therapy
, 2009 The efficacy of cardiac resynchronization therapy (CRT) through biventricular pacing (BVP) has been demonstrated by numerous studies in patients suffering from congestive heart failure. In order to achieve a guideline for optimal treatment with BVP devices, an automated non-invasive strategy based on an electrophysiological computer model of the heart ...
openaire +1 more source