Results 81 to 90 of about 282,561 (345)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Optic and motor alteration in Balint syndrome: computer assisted occupational therapy
European Journal of Human Movement, 2010 Balint Syndrome, which was reported in 1909, is an affection produced by bilateral parieto-occipital lesions affecting the connections between the visual cortical regions and the prerolandic motor areas and caracterized by visual ataxia, failure to grasp
L.P. Rodríguez, R. Moreno, C. Flórez
doaj
Neuraltherapy Treatment of Shoulder Periarthritis: A Case Report
Medicine Science, 2015 In recent years, increasing importance worldwide has been given to treatment with natural methods, also known as complementary medicine. Currently, there are 18 sub-branches of treatment; neuraltherapy, acupuncture, phytotherapy, ozone therapy, manual ...
Tuba Tulay Koca
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
, 1998 The contemporary practice of psychology requires a prudent balance of traditional and emerging communication methods. Interpersonal interactions in the context of human relationship (e.g., speech, emotional expressions, and nonverbal gestures) have been ...
McMinn, Mark R
core
Using technology to deliver cancer follow-up : a systematic review [PDF]
, 2014 Peer reviewedPublisher ...
A Allen +45 more
core +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Predicting progression events in multiple myeloma from routine blood work
npj Digital MedicineThis study introduces a system for predicting disease progression events in multiple myeloma patients from the CoMMpass study (N = 1186). Utilizing a hybrid neural network architecture, our model predicts future blood work from historical lab results ...
Maximilian Ferle +11 more
doaj +1 more source
, 2017 Autonomous surgery involves having surgical tasks performed by a robot operating under its own will, with partial or no human involvement. There are several important advantages of automation in surgery, which include increasing precision of care due to ...
Das, Nikhil, Yip, Michael
core +1 more source