Results 101 to 110 of about 2,182,933 (405)

Computer Aided Aroma Design. II. Quantitative structure-odour relationship [PDF]

open access: yes, 2008
Computer Aided Aroma Design (CAAD) is likely to become a hot issue as the REACH EC document targets many aroma compounds to require substitution. The two crucial steps in CAMD are the generation of candidate molecules and the estimation of properties ...
Floquet, Pascal   +5 more
core   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Dual modality prompt learning for visual question-grounded answering in robotic surgery

open access: yesVisual Computing for Industry, Biomedicine, and Art
With recent advancements in robotic surgery, notable strides have been made in visual question answering (VQA). Existing VQA systems typically generate textual answers to questions but fail to indicate the location of the relevant content within the ...
Yue Zhang   +5 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Marginal accuracy of computer-aided design- and computer-aided manufacturing-fabricated full-arch zirconia restoration

open access: yesClinical, Cosmetic and Investigational Dentistry, 2018
Niwut Juntavee,1 Issarawas Sirisathit2 1Department of Prosthodontics, 2Division of Biomaterials and Prosthodontics Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand Objective: This study evaluated marginal accuracy of full-arch ...
Juntavee N, Sirisathit I
doaj  

A modern course on digital design at the University of Twente [PDF]

open access: yes, 1992
At the University of Twente, the Netherlands a modern course on basic digital design has been developed. This course, which is based on a text book in English (K. J.
Beusekamp, M.F.
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Improved Adaptive Routing Algorithm in Distributed Data Centers

open access: yesAdvances in Electrical and Electronic Engineering, 2017
Currently, telecom operators use virtualization of network infrastructure based on Data Centers (DCs). But when a company grows to a certain size and one DC is not sufficient, there are questions how to further develop the network infrastructure.
Dmitry Perepelkin, Maria Ivanchikova
doaj   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

Biodynamics of supine humans and interaction with transport systems during vibration and shocks

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2019
This work investigates the effect of the contact surfaces on the biomechanical response of supine humans during whole-body vibration and shocks. Twelve participants were exposed to three-dimensional random vibration and shocks and were tested with two ...
Salam Rahmatalla   +2 more
doaj   +1 more source

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