Results 121 to 130 of about 2,182,933 (405)
IPAD: A unique approach to government/industry cooperation for technology development and transfer [PDF]
A key element to improved industry productivity is effective management of Computer Aided Design / Computer Aided Manufacturing (CAD/CAM) information. To stimulate advancement, a unique joint government/industry project designated Integrated Programs for
Fulton, Robert E., Salley, George C.
core +1 more source
Expanding Biosensing Abilities through Computer-Aided Design of Metabolic Pathways.
ACS Synthetic Biology, 2016 Detection of chemical signals is critical for cells in nature as well as in synthetic biology, where they serve as inputs for designer circuits. Important progress has been made in the design of signal processing circuits triggering complex biological ...
Vincent K Libis +2 more
semanticscholar +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Magnetic Flux Sensor Based on Spiking Neurons with Josephson Junctions
SensorsJosephson junctions (JJs) are superconductor-based devices used to build highly sensitive magnetic flux sensors called superconducting quantum interference devices (SQUIDs).
Timur Karimov +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Maxillofacial plastic and reconstructive surgery, 2016 We reviewed the biological and mechanical properties of porous hydroxyapatite (HA) compared to other synthetic materials. Computer-aided design/computer-aided manufacturing (CAD/CAM) was also evaluated to estimate its efficacy with clinical and ...
U. Garagiola +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Time-Series Feature Extraction by Return Map Analysis and Its Application to Bearing-Fault Detection
Big Data and Cognitive ComputingDeveloping new features for time-series characterization is a current challenge in data science and machine learning. In this paper, we propose a new metric based on a simple and efficient algorithm, namely, the return map.
Veronika Ponomareva +6 more
doaj +1 more source