Results 131 to 140 of about 2,182,933 (405)

Compact Manufacturing Systems Structural Synthesis Automation

open access: yesCommunications, 2000
In the paper the problems of collective designing of modern industrial systems in the "Lean Production" concept are considered. The definition of compact manufacturing system (CMS) is given, and the original principles of industrial compactness ...
Dmitry Svirsky
doaj   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Computer-aided molecular design

open access: yesComputer-Aided Design, 1985
Abstract Computer-aided molecular design has come of age. In the pharmaceutical and fine chemical industries computer graphics techniques allied to theoretical calculations are proving successful in suggesting to synthetic chemists molecules which will merit synthesis in terms of desired specific properties.
openaire   +3 more sources

FEATURES OF THE MANAGEMENT OF DATA ENCRYPTION KEYS IN THE CLOUD STORAGE MS SQL AZURE

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2018
The main principles of data security and access organization in the Microsoft Azure cloud storage are considered. A role of hierarchy and access keys are presented.
Olexander Beley
doaj   +1 more source

Geometric modeling for computer-aided design [PDF]

open access: yes
Software was developed to be used with the derivation of smooth three dimensional surfaces from a sequence of cross sections. Problems arising in the creation of surfaces by extrusion are considered and calculated physical properties are ...
Schwing, James L., Spangler, Jan
core   +1 more source

COMPUTER AIDED DRUG DESIGN: AN OVERVIEW

open access: yesJournal of Drug Delivery and Therapeutics, 2018
Discovery and development of a new drug is generally known as a very complex process which takes a lot of time and resources. So now a day’s computer aided drug design approaches are used very widely to increase the efficiency of the drug discovery and ...
Surabhi Surabhi, B. Singh
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Geometric Deep Learning for Computer-Aided Design: A Survey [PDF]

open access: yesarXiv
Geometric Deep Learning techniques have become a transformative force in the field of Computer-Aided Design (CAD), and have the potential to revolutionize how designers and engineers approach and enhance the design process. By harnessing the power of machine learning-based methods, CAD designers can optimize their workflows, save time and effort while ...
arxiv  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

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