Results 151 to 160 of about 2,182,933 (405)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Computer Aided Drug Designing

International Journal of Medical and Dental Sciences, 2017
Designing of drugs and their development are a time and resource consuming process. There is an increasing effort to introduce the role of computational approach to chemical and biological space in order to organise the design and development of drugs and their optimisation.
Supratik Das, Anand Vardhan, Vijay K. Sehgal   +2 more
openaire   +3 more sources

CADgpt: Harnessing Natural Language Processing for 3D Modelling to Enhance Computer-Aided Design Workflows [PDF]

arXiv
This paper introduces CADgpt, an innovative plugin integrating Natural Language Processing (NLP) with Rhino3D for enhancing 3D modelling in computer-aided design (CAD) environments. Leveraging OpenAI's GPT-4, CADgpt simplifies the CAD interface, enabling users, particularly beginners, to perform complex 3D modelling tasks through intuitive natural ...
arxiv  

Time-shared computer aided design with the digital plotters [PDF]

, 1969
Robert J. Cowan
openalex   +1 more source

Computer-aided design and analysis of circuits and systems Final report, 20 Sep. 1966 - 1 Jul. 1968 [PDF]

Consolidation, standardization, and qualification of computer program routines associated with computer-aided design and analysis of circuits and ...
Henry, E. W.
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Development and Evaluation of a Personalized Computer-aided Question Generation for English Learners to Improve Proficiency and Correct Mistakes [PDF]

arXiv, 2018
In the last several years, the field of computer assisted language learning has increasingly focused on computer aided question generation. However, this approach often provides test takers with an exhaustive amount of questions that are not designed for any specific testing purpose.
arxiv  

Computer aided logic design [PDF]

, 1972
Frank W. Bliss
openalex   +1 more source

CA-Techniken und CIM [PDF]

, 1991
Der Arbeitsbericht gibt zunächst einen Überblick über die technisch orientierten rechnergestützten Komponenten im Rahmen des Computer Integrated Manufacturing (CIM), die sogenannten CAx-Systeme oder CA-Systeme: CAD (Computer Aided Design) CAP (Computer ...
Kurbel, Karl
core  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source