Results 171 to 180 of about 2,182,933 (405)

Variable-Step Semi-Implicit Solver with Adjustable Symmetry and Its Application for Chaos-Based Communication

open access: yesMathematics
In this article, we introduce a novel approach to numerical integration based on a modified composite diagonal (CD) method, which is a variation of the semi-implicit Euler–Cromer method.
Vyacheslav Rybin   +5 more
doaj   +1 more source

Multiobjective gas turbine engine controller design using genetic algorithms

open access: yes, 1996
This paper describes the use of multiobjective genetic algorithms (MOGAs) in the design of a multivariable control system for a gas turbine engine. The mechanisms employed to facilitate multiobjective search with the genetic algorithm are described with ...
Chipperfield, A., Fleming, P.
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Therapeutic Potential of Antiviral Peptides against the NS2B/NS3 Protease of Zika Virus

open access: yesACS Omega, 2023
Md. Shahadat Hossain   +10 more
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

A bibliography on digital computer-aided circuit analysis and design [PDF]

open access: yes
Digital computer-aided electric logic circuit analysis and design ...
Yang, T.
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

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