Results 21 to 30 of about 593,733 (340)

How neocarcerand Octacid4 self-assembles with guests into irreversible noncovalent complexes and what accelerates the assembly

Communications Chemistry, 2022
Neocarcerand Octacid4 can assemble with small molecule guests at room temperature to produce irreversible noncovalent bimolecular complexes, but the nature of the self-assembly pathway remains poorly understood.
Yuan-Ping Pang
doaj   +1 more source

Computer-aided verification in mechanism design

, 2015
In mechanism design, the gold standard solution concepts are dominant strategy incentive compatibility and Bayesian incentive compatibility. These solution concepts relieve the (possibly unsophisticated) bidders from the need to engage in complicated ...
AV Goldberg, C Daskalakis, EH Clarke, G Barthe, G Barthe, M Bellare, T Groves, T Roughgarden, T Sandholm, W Vickrey   +9 more
core   +4 more sources

Using Computer Technology Tools to Improve the Teaching-Learning Process in Technical and Vocational Education: Mechanical Engineering Subject Area [PDF]

, 2009
This paper discusses the integration of computer assisted instructions (CAI) with traditional class room teaching. It describes a teaching method to bring real-world of industrial work into the classroom that underscores the need to learn fundamental ...
Abdulrasool, Salah Mahdi, Mishra, Rakesh
core   +1 more source

hERG Blockade Prediction by Combining Site Identification by Ligand Competitive Saturation and Physicochemical Properties

Chemistry, 2022
The human ether-a-go-go-related gene (hERG) potassium channel is a well-known contributor to drug-induced cardiotoxicity and therefore is an extremely important target when performing safety assessments of drug candidates.
Himanshu Goel, Wenbo Yu, Alexander D. MacKerell   +2 more
doaj   +1 more source

Identification of the viscoelastic boundary conditions of Euler‐Bernoulli beams using transmissibility

Engineering Reports, 2019
A new method to identify the viscoelastic boundary conditions of Euler‐Bernoulli beams under forced response is here presented. The boundary conditions and transmissibility function with viscoelastic expressions in terms of the Green function are ...
Guandong Qiao, Salam Rahmatalla
doaj   +1 more source

Computer Aided Aroma Design. II. Quantitative structure-odour relationship [PDF]

, 2008
Computer Aided Aroma Design (CAAD) is likely to become a hot issue as the REACH EC document targets many aroma compounds to require substitution. The two crucial steps in CAMD are the generation of candidate molecules and the estimation of properties ...
Floquet, Pascal, Gerbaud, Vincent, Korichi, Mourad, Meniai, A.-Hassan, Nacef, Saci, Talou, Thierry   +5 more
core   +2 more sources

The Effect of Using Computer Technology Tools to Enhance the Teaching-Learning Process in CAD-CAM-CNC Module in Mechanical Engineering Subject Area [PDF]

, 2010
This study presents the evaluation of Computer Assisted Learning (CAL) package included in the teaching and learning methodology of computer aided design- computer aided design - computer numerical control (CAD-CAM-CNC) module.
Abdulrasool, Salah Mahdi, Al Seddiqi, Mohamed, Khalaf, Haifa, Mishra, Rakesh   +3 more
core  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Efficient workflow scheduling using an improved multi-objective memetic algorithm in cloud-edge-end collaborative framework

Scientific Reports
With the rapid advancement of large-scale model technologies, AI agent frameworks built on foundation models have become a central focus of artificial-intelligence research.
Guangzhang Cui, Wei Zhang, Weiwei Xu, Hujun Bao   +3 more
doaj   +1 more source