Results 31 to 40 of about 622,360 (336)

hERG Blockade Prediction by Combining Site Identification by Ligand Competitive Saturation and Physicochemical Properties

Chemistry, 2022
The human ether-a-go-go-related gene (hERG) potassium channel is a well-known contributor to drug-induced cardiotoxicity and therefore is an extremely important target when performing safety assessments of drug candidates.
Himanshu Goel, Wenbo Yu, Alexander D. MacKerell   +2 more
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Computer-aided molecular design

Computer-Aided Design, 1985
Abstract Computer-aided molecular design has come of age. In the pharmaceutical and fine chemical industries computer graphics techniques allied to theoretical calculations are proving successful in suggesting to synthetic chemists molecules which will merit synthesis in terms of desired specific properties.
openaire   +2 more sources

Space station models, mockups and simulators [PDF]

, 1985
Schematic outlines for space station models, mockups, and simulators are presented. The types of Boeing models, mockups, and simulators are given along with the classes and characteristics.
Miller, K. H., Osgood, A.
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Computer-aided identification of Neisseria gonorrhoeae’s Bacteriophage-Q-beta inhibitors from selected anti-gonorrheal plants

Discover Chemistry
The emergence of multidrug-resistant Neisseria gonorrhoeae has intensified the need for innovative therapeutic strategies. One promising but underexplored target is the Hfq protein, a key regulator in bacterial stress response and pathogenesis.
Badmus Jamiu Damilare, Che Muhammad Khairul-Hisyam Ismail, Blessing O. Awoyemi, Abdullahi Tunde Aborode, Ibukun Faith Michael, Haruna Isiyaku Umar, Omoboyede Victor, Zainab Naeem Abdulsalam, Oluwabusayo Olufunke Awoyomi, Sodiq Fakorede, Ousainou Gomez, Adekunle Adeoye, Olasehinde Omolayo, Isreal Ayobami Onifade, Abdullahi Temitope Jamiu   +14 more
doaj   +1 more source

Convolutional Autoencoder-Based Method for Predicting Faults of Cyber-Physical Systems Based on the Extraction of a Semantic State Vector

Machines
Modern industrial equipment is a cyber-physical system (CPS) consisting of physical production components and digital controls. Lowering maintenance costs and increasing availability is important to improve its efficiency.
Konstantin Zadiran, Maxim Shcherbakov
doaj   +1 more source

Design of a Smart Bartender with Peristaltic Pumps

Inventions, 2019
In this paper, the development of a smart scalable system for liquid supply based on high-precision peristaltic pumps is described. The architecture of software and hardware for the proposed system is considered. This liquid supply system can be used for
Vyacheslav Rybin, Timur Karimov, Maria Sigaeva, Ekaterina Solomevich, Georgii Kolev, Ekaterina Kopets   +5 more
doaj   +1 more source

Computer Aided Design / Computer Aided Manufactur [CAD/CAM] [PDF]

, 2005
Computer-aided design (CAD) atau computer-aided design and drafting (CADD), merupakan satu bentuk otomatisasi yang membantu perancang untuk memperbaiki gambar, spesifikasi, dan elemen-elemen yang berhubungan dengan perancangan yang menggunakan efek ...
N, D. H. (Dewi)
core  

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source