Results 31 to 40 of about 898,999 (335)

Industrial Environmental Impact Assessment Method Based on Detection of Complex Anomalies in Time Series

Applied System Innovation
To minimize the environmental impact of energy enterprises, it is important to promptly identify cases of possible changes in the quality of wastewater generated at power plants, that is, cases of exceeding the maximum permissible concentrations of ...
Elena Safonova, Alla Kravets, Maxim Shcherbakov, Alexey Kizim, Mohammad Al-Gunaid, Alexander Echin   +5 more
doaj   +1 more source

How neocarcerand Octacid4 self-assembles with guests into irreversible noncovalent complexes and what accelerates the assembly

Communications Chemistry, 2022
Neocarcerand Octacid4 can assemble with small molecule guests at room temperature to produce irreversible noncovalent bimolecular complexes, but the nature of the self-assembly pathway remains poorly understood.
Yuan-Ping Pang
doaj   +1 more source

Computer-Aided Design of Microfluidic Circuits.

Annual Review of Biomedical Engineering, 2020
Microfluidic devices developed over the past decade feature greater intricacy, increased performance requirements, new materials, and innovative fabrication methods.
Elishai Ezra Tsur
semanticscholar   +1 more source

Identification of the viscoelastic boundary conditions of Euler‐Bernoulli beams using transmissibility

Engineering Reports, 2019
A new method to identify the viscoelastic boundary conditions of Euler‐Bernoulli beams under forced response is here presented. The boundary conditions and transmissibility function with viscoelastic expressions in terms of the Green function are ...
Guandong Qiao, Salam Rahmatalla
doaj   +1 more source

hERG Blockade Prediction by Combining Site Identification by Ligand Competitive Saturation and Physicochemical Properties

Chemistry, 2022
The human ether-a-go-go-related gene (hERG) potassium channel is a well-known contributor to drug-induced cardiotoxicity and therefore is an extremely important target when performing safety assessments of drug candidates.
Himanshu Goel, Wenbo Yu, Alexander D. MacKerell   +2 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Efficient workflow scheduling using an improved multi-objective memetic algorithm in cloud-edge-end collaborative framework

Scientific Reports
With the rapid advancement of large-scale model technologies, AI agent frameworks built on foundation models have become a central focus of artificial-intelligence research.
Guangzhang Cui, Wei Zhang, Weiwei Xu, Hujun Bao   +3 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Design of a Smart Bartender with Peristaltic Pumps

Inventions, 2019
In this paper, the development of a smart scalable system for liquid supply based on high-precision peristaltic pumps is described. The architecture of software and hardware for the proposed system is considered. This liquid supply system can be used for
Vyacheslav Rybin, Timur Karimov, Maria Sigaeva, Ekaterina Solomevich, Georgii Kolev, Ekaterina Kopets   +5 more
doaj   +1 more source