Results 51 to 60 of about 2,182,933 (405)

A simple anthropometric estimation formula for healthy female labourers’ leg volume

open access: yesAnnals of Human Biology, 2023
Background Leg volume (LV) is an important reference in nutrition, physiology in exercise, or clinical diagnosis. Therefore, how to evaluate LV easily and quickly with accuracy is important in these areas.
Hsin-Hung Tu
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Knitting Skeletons: A Computer-Aided Design Tool for Shaping and Patterning of Knitted Garments [PDF]

open access: yesACM Symposium on User Interface Software and Technology, 2019
This work presents a novel interactive system for simple garment composition and surface patterning. Our approach makes it easier for casual users to customize machine-knitted garments, while enabling more advanced users to design their own composable ...
Alexandre Kaspar   +2 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Discoloration Resistance of Various Computer Aided Design/Computer Aided Manufacturing Restorative Materials

open access: yesEssentials of Dentistry
Background: Evaluating the prolonged efficacy of restorative materials hinges significantly on their ability to resist discoloration. This study aims to assess the discoloration resistance of computer-aided design/computer-aided manufacturing restorative
Rana Turunç Oğuzman   +1 more
doaj   +1 more source

Small Molecule Targeting of Protein–Protein Interactions through Allosteric Modulation of Dynamics

open access: yesMolecules, 2015
The protein–protein interaction (PPI) target class is particularly challenging, but offers potential for “first in class” therapies. Most known PPI small molecules are orthosteric inhibitors but many PPI sites may be fundamentally intractable to this ...
Benjamin P. Cossins   +1 more
doaj   +1 more source

A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein

open access: yesCell Death Discovery, 2021
Increasing evidence suggests the pivotal role of hematopoietic pre-B-cell leukemia transcription factor (PBX)-interacting protein (HPIP/PBXIP1) in cancer development and progression, indicating that HPIP inhibition may be a promising target for cancer ...
Pengyun Li   +12 more
doaj   +1 more source

Interactive graphical computer-aided design system [PDF]

open access: yes, 1975
System is used for design, layout, and modification of large-scale-integrated (LSI) metal-oxide semiconductor (MOS) arrays. System is structured around small computer which provides real-time support for graphics storage display unit with keyboard, slave
Edge, T. M.
core   +1 more source

Computer Aided Aroma Design. I. Molecular knowledge framework [PDF]

open access: yes, 2008
Computer Aided Aroma Design (CAAD) is likely to become a hot issue as the REACH EC document targets many aroma compounds to require substitution. The two crucial steps in CAMD are the generation of candidate molecules and the estimation of properties ...
Floquet, Pascal   +5 more
core   +1 more source

Recent advances in the reconstruction of cranio-maxillofacial defects using computer-aided design/computer-aided manufacturing

open access: yesMaxillofacial plastic and reconstructive surgery, 2018
With the development of computer-aided design/computer-aided manufacturing (CAD/CAM) technology, it has been possible to reconstruct the cranio-maxillofacial defect with more accurate preoperative planning, precise patient-specific implants (PSIs), and ...
Ji-hyeon Oh
semanticscholar   +1 more source

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