Results 61 to 70 of about 2,182,933 (405)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Computer-aided whole-cell design: taking a holistic approach by integrating synthetic with systems biology [PDF]

arXiv, 2020
Computer-aided design for synthetic biology promises to accelerate the rational and robust engineering of biological systems; it requires both detailed and quantitative mathematical and experimental models of the processes to (re)design, and software and tools for genetic engineering and DNA assembly.
arxiv  

Comparing Neural Style Transfer and Gradient-Based Algorithms in Brushstroke Rendering Tasks

Mathematics, 2023
Non-photorealistic rendering (NPR) with explicit brushstroke representation is essential for both high-grade imitating of artistic paintings and generating commands for artistically skilled robots.
Artur Karimov, Ekaterina Kopets, Tatiana Shpilevaya, Evgenii Katser, Sergey Leonov, Denis Butusov   +5 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Semi-Implicit Multistep Extrapolation ODE Solvers

Mathematics, 2020
Multistep methods for the numerical solution of ordinary differential equations are an important class of applied mathematical techniques. This paper is motivated by recently reported advances in semi-implicit numerical integration methods, multistep and
Denis Butusov, Aleksandra Tutueva, Petr Fedoseev, Artem Terentev, Artur Karimov   +4 more
doaj   +1 more source

Unraveling the multi-targeted curative potential of bioactive molecules against cervical cancer through integrated omics and systems pharmacology approach

Scientific Reports, 2022
Molecular level understanding on the role of viral infections causing cervical cancer is highly essential for therapeutic development. In these instances, systems pharmacology along with multi omics approach helps in unraveling the multi-targeted ...
Murali Aarthy, Pandiyan Muthuramalingam, Manikandan Ramesh, Sanjeev Kumar Singh   +3 more
doaj   +1 more source

Современные подходы в 3D моделировании ортезных приспособлений [PDF]

, 2014
Рассмотрены технологические решения моделирования и изготовления ортезных приспособлений с использованием систем автоматизированного проектирования группы CAD (Computer Aided Design) – CAM (Computer Aided Design).The technological decisions of design and
Носов, П. С., Яковенко, А. Е.   +1 more
core  

Computer-Aided Test Flow in Core-Based Design [PDF]

, 2000
This paper copes with the test-pattern generation and fault coverage determination in the core based design. The basic core-test strategy that one has to apply in the core-based design is stated in this work.
Kerkhoff, H.G., Tangelder, R.J.W.T., Zivkovic, V.A.   +2 more
core   +4 more sources

A review of computer-aided design/computer-aided manufacture techniques for removable denture fabrication

European Journal of Dentistry, 2016
The aim of this review was to investigate usage of computer-aided design/computer-aided manufacture (CAD/CAM) such as milling and rapid prototyping (RP) technologies for removable denture fabrication.
M. Bilgin, Ebru Nur Baytaroğlu, A. Erdem, Erhan Dilber   +3 more
semanticscholar   +1 more source

Boosting human decision-making with AI-generated decision aids [PDF]

arXiv, 2022
Human decision-making is plagued by many systematic errors. Many of these errors can be avoided by providing decision aids that guide decision-makers to attend to the important information and integrate it according to a rational decision strategy. Designing such decision aids used to be a tedious manual process.
arxiv