Results 181 to 190 of about 2,465,886 (354)
EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot +36 morewiley +1 more sourceEngineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang +12 morewiley +1 more sourceInterrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne +61 morewiley +1 more sourceComputer Science & Information Technology (CS & IT) [PDF]
, 2017 Natarajan Meghanathan, Brajesh Kaushik, Abdelghani Ghazdali, Abdelilah Hakim, Aihua Mao, Bartholomew Placzek, Bernardo Almada, Chen Haishan, Chin-Chen Chang, Feng Chia, Chuanzong Zhang, Damian Ruiz, Deng Li, Emad Eldin, Emilio Serrano, Fatma Outay, Guilherme Oliveira, Hamid Alasadi, Hamzeh Khalili, Hao-En Chueh, Hari Garg, Ismail Shahin, Issac Swamidoss, Jagadish Nayak, Jiahua Zhu, Jitender Grover, Joao Gama, Lei Zhang, Yuhanis Madya, Binti Yusof, Mahmoud Delavar, Mamoun Helou, Manish Mishra, Marta Ruiz, Mike Turi, Milo Brajovic, Mimoun Hamdi, Mohamed Mellal, Mohamed Fakhr, Mohammad Shayegan, Mohammad Sattari, Nadjia Benblidia, Nayeem Khan, Robert Istepanian, Roco Prez, Songling Huang, Tayebeh Askari, Thai-Son Nguyen, Yang Li, Yuan Zhuang, Yu-Chen Hu, Yue Cao, Zbigniew Banaszak, Jean Tajer, Mo Adda, Benjamin Aziz, Mohamed Bouatit, Selma Boumerdassi, Mrs Shahanaz, Mrs Greeshma, Moneef Almutairi, Stephen Riddle, Mostafa Hefnawi, Brajesh Kumar, D Moore, G Voelker, S Savage, Jiang-Ping Hu, Jin Zhi-Xinliu, Huanwang, Wang Lin, Xiao-Ming Hu, O Salem, S Vaton, A Gravey, G Cormode, S Muthukrishnan, J Tang, Y Cheng, C Zhou, M Broniatowski, S Leorato, J Havrda, F Chavrat, P Rathie, P Kannappan, D Haussler, M Opper, Mohamed Nassar, Radu State, Olivier Festor, V Jacobson, Tascos Dagiuklzd, Jiri Markl, Michal Rokos, Hemant Sengar, Duminda Wijesekera, Sushil Jjodia, Guido Van 't Noordende, Frances Brazier +99 moreopenalex +3 more sources
