Results 271 to 280 of about 2,465,886 (354)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Advancing Personalized Strategies for Obesity Prevention Through Biologically and Behaviorally Tailored Interventions: The Strategic Framework for the BETTER4U Initiative. [PDF]

Obes Rev
Kafyra M, Kalafati IP, Bruins S, Episkopou C, Gryspeerdt D, Heggie L, Kaltenbrunner S, Kampshoff S, Karaglani E, Prändl HÖ, Papathanail I, Symianakis PG, Silchenko D, Vavouraki V, Boomsma D, Delopoulos A, Diou C, Eriksson A, Kaprio J, Krzywicka P, Luszczynska A, Manios Y, Marouli E, Moulos P, Mougiakakou S, Pool R, Silventoinen K, Verhaege N, Willems R, Dedoussis GV, BETTER4U consortium.   +30 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Communications in Computer and Information Science Security in Computer and Information Sciences

openaire   +2 more sources

Author Correction: Temporal structure of natural language processing in the human brain corresponds to layered hierarchy of large language models. [PDF]

Nat Commun
Goldstein A, Ham E, Schain M, Nastase SA, Aubrey B, Zada Z, Grinstein-Dabush A, Gazula H, Feder A, Doyle W, Devore S, Dugan P, Friedman D, Brenner M, Hassidim A, Matias Y, Devinsky O, Siegelman N, Flinker A, Levy O, Reichart R, Hasson U.   +21 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

EFFECT OF COMPUTER-ASSISTED INSTRUCTION ON THE PERFORMANCE OF LIBRARY AND INFORMATION SCIENCE UNDERGRADUATESIN DELTA STATE UNIVERSITY, ABRAKA

, 2020
Ogochukwu Thaddaeus Emiri
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Multi-adaptive event-triggered consensus of positive multi-agent systems using pinning strategy. [PDF]

PLoS One
Li Q, Dong L, Yang H.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source