Results 151 to 160 of about 260,987 (350)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Substantial differences in fault levels between grid-tied and islanded modes is one of the primary challenges of microgrid protection. During grid-tied mode, the bulk grid provides significant short-circuit, while during islanded operation the short ...
Maximiliano Ferrari +2 more
doaj +1 more source
Modes of Interaction in Computational Architecture
This thesis is an enquiry into the importance and influence of interaction in architecture, the importance of which is observed through different modes of interaction occurring in various aspects of architectural discourse and practice.
Antic, Dragana Cebzan
core
Introduction to Computer Systems and Programming in Architecture and Construction
An introductory computer text for undergraduate students in architecture, architectural engineering, construction, landscape and planning. It provides working knowledge of BASIC and FORTRAN, using small computer program as an educational tool to ...
J. Conrad, J. Pohl
core
Pattern-based software architecture for service-oriented software systems [PDF]
Service-oriented architecture is a recent conceptual framework for service-oriented software platforms. Architectures are of great importance for the evolution of software systems.
Pahl, Claus, Barrett, Ronan
core
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
A conceptual system design and managerial complexity competency model [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Complex adaptive systems are usually difficult to design and control.
Amaechi, Austin Oguejiofor
core
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
M2: An architectural system for computer design
ion Representation Compilation ARCHITECTURE Structure Organization Behavior IMPLEMENTATION Technology Physical ...
openaire +2 more sources

