Results 121 to 130 of about 778,717 (328)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Three Dimensional Digitally Designed Surgical Guides in Esthetic Crown Lengthening: A Clinical Case Report with 12 Months Follow Up

open access: yesClinical, Cosmetic and Investigational Dentistry, 2022
Saad Obaid Alazmi Department of Periodontology & Oral Medicine, College of Dentistry, Qassim University, Burayadh, Qassim, Saudi ArabiaCorrespondence: Saad Obaid AlazmiDepartment of Periodontology & Oral Medicine, College of Dentistry, Qassim University,
Alazmi SO
doaj  

External Resource Annotation Framework and its applications in E-learning

open access: yesInteraction Design and Architecture(s), 2016
Rich Internet Applications that enable new ways of interaction with digital objects within multimedia scenes become important for educational communities.
Roxana Moldovan   +4 more
doaj   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Joint Time-Frequency-Space Classification of EEG in a Brain-Computer Interface Application

open access: yesEURASIP Journal on Advances in Signal Processing, 2003
Brain-computer interface is a growing field of interest in human-computer interaction with diverse applications ranging from medicine to entertainment.
Molina Gary N Garcia   +2 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Computational Methods in Biophysics and Medicinal Chemistry: Applications and Challenges

open access: yes, 2014
In this thesis I described the theory and application of several computational methods in solving medicinal chemistry and biophysical tasks. I pointed out to the valuable information which could be achieved by means of computer simulations and to the possibility to predict the outcome of traditional experiments.
Di Martino, Giovanni Paolo
openaire   +2 more sources

Home - About - Disclaimer - Privacy