Results 51 to 60 of about 778,717 (328)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Digital Twin Technology: The Future of Predicting Neurological Complications of Pediatric Cancers and Their Treatment

open access: yesFrontiers in Oncology, 2022
Healthcare technologies have seen a surge in utilization during the COVID 19 pandemic. Remote patient care, virtual follow-up and other forms of futurism will likely see further adaptation both as a preparational strategy for future pandemics and due to ...
Grace M. Thiong’o   +3 more
doaj   +1 more source

The state of quantum computing applications in health and medicine

open access: yesResearch Directions: Quantum Technologies, 2023
Abstract Quantum computing hardware and software have made enormous strides over the last years1. Questions around quantum computing’s impact on research and society have changed from “if” to “when/how”. The 2020s have been described as the “quantum decade”, and the first production solutions that drive scientific and business value are expected to ...
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine [PDF]

open access: yes, 2003
This book examines the applications of Monte Carlo (MC) calculations in therapeutic nuclear medicine, from basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning.
Sgouros, George, Zaidi, Habib
core  

Applications of artificial intelligence in orthopaedic surgery

open access: yesFrontiers in Medical Technology, 2022
The practice of medicine is rapidly transforming as a result of technological breakthroughs. Artificial intelligence (AI) systems are becoming more and more relevant in medicine and orthopaedic surgery as a result of the nearly exponential growth in ...
Faraz Farhadi   +6 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Computer application of ultrasound and nuclear magnetic resonance images for the anatomical learning of the pelvis and the female pelvic floor [PDF]

open access: yes, 2019
[EN]Computer applications have been incorporated as valuable components in teaching, especially thanks to the advancement and innovation of new technologies during the last decades.
Asensio Gómez, Manuel   +3 more
core   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

ART Neural Networks: Distributed Coding and ARTMAP Applications [PDF]

open access: yes, 2000
ART (Adaptive Resonance Theory) neural networks for fast, stable learning and prediction have been applied in a variety of areas. Applications include airplane design and manufacturing, automatic target recognition, financial forecasting, machine tool ...
Carpenter, Gail
core   +2 more sources

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