Results 81 to 90 of about 88,955,851 (279)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Digest of the Philadelphia College of Osteopathic Medicine (Winter 1991) [PDF]

open access: yes, 1991
The Winter 1991 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles: A Master Plan to Grow on: City Avenue Campus Emanuel Fliegelman, DO: Reminding Us That to be Human is to be Best PCOM\u27s Computer
Philadelphia College of Osteopathic Medicine
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Computer applications as a high school graduation requirement [PDF]

open access: yes, 2001
Plan BComputer use in the educational setting is a topic of much research, teacher concern, and debate at the national, state, and district level.
Stone, Keith G.
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Artificial Intelligence and Vascular Surgery

open access: yesIndian Journal of Vascular and Endovascular Surgery
Artificial intelligence (AI) is a science where computer programs perform tasks that typically require human intelligence. AI technologies and machine learning applications have resulted in exponential technical advancement in the field of medicine ...
Manvendu Jha   +2 more
doaj   +1 more source

Leukemia [PDF]

open access: yes, 2003
The transcript of a Witness Seminar held at the Wellcome Trust Centre for the History of Medicine at UCL, London, on 15 May 2001.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2003.©The Trustee of the Wellcome Trust ...
Christie, DA, Tansey, EM
core   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Technological innovation and future development of quantitative research on acupuncture manipulation techniques

open access: yes针刺研究
The quantitative research on acupuncture manipulation techniques aims to transform traditional empirical operations into measurable parameters through interdisciplinary technologies.
GAO Jun-hong   +3 more
doaj  

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