Results 81 to 90 of about 88,955,851 (279)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Digest of the Philadelphia College of Osteopathic Medicine (Winter 1991) [PDF]
The Winter 1991 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles: A Master Plan to Grow on: City Avenue Campus Emanuel Fliegelman, DO: Reminding Us That to be Human is to be Best PCOM\u27s Computer
Philadelphia College of Osteopathic Medicine
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Computer applications as a high school graduation requirement [PDF]
Plan BComputer use in the educational setting is a topic of much research, teacher concern, and debate at the national, state, and district level.
Stone, Keith G.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Artificial Intelligence and Vascular Surgery
Artificial intelligence (AI) is a science where computer programs perform tasks that typically require human intelligence. AI technologies and machine learning applications have resulted in exponential technical advancement in the field of medicine ...
Manvendu Jha +2 more
doaj +1 more source
The transcript of a Witness Seminar held at the Wellcome Trust Centre for the History of Medicine at UCL, London, on 15 May 2001.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2003.©The Trustee of the Wellcome Trust ...
Christie, DA, Tansey, EM
core +3 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The quantitative research on acupuncture manipulation techniques aims to transform traditional empirical operations into measurable parameters through interdisciplinary technologies.
GAO Jun-hong +3 more
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