Results 81 to 90 of about 24,050 (249)

Evaluation of Perkin Elmer Amorphous Silicon Electronic Portal Imaging Device for Small Photon Field Dosimetry [PDF]

open access: yesJournal of Biomedical Physics and Engineering
Background: Electronic portal imaging devices (EPIDs) are applied to measure the dose and verify patients’ position.Objective: The present study aims to evaluate the performance of EPID for measuring dosimetric parameters in small photon fields.Material ...
Mohammad Haghparast   +4 more
doaj   +1 more source

Focal Spot, Winter 1986 [PDF]

open access: yes, 1986
https://digitalcommons.wustl.edu/focal_spot_archives/1042/thumbnail ...

core   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

open access: yesAdvanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez   +17 more
wiley   +1 more source

Evaluation of a Treatment Planning System for Applying the Effect of Titanium Clips on Isodosedistribution in Radiation Therapy of Colorectal Cancer

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: In laparoscopy of colorectal tumors, titanium clips are used to close the surgery site. For post-operation treatment with radiation, the clips might change the dose distribution.
Razieh Karimi   +4 more
doaj  

Organ at Risk Segmentation in Head and Neck CT Images Using a Two-Stage Segmentation Framework Based on 3D U-Net

open access: yesIEEE Access, 2019
Accurate segmentation of organs at risk (OARs) plays a critical role in the treatment planning of image-guided radiotherapy of head and neck cancer. This segmentation task is challenging for both humans and automated algorithms because of the relatively ...
Yueyue Wang   +3 more
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

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