The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Thesis (M.E.)--Dept. of Electrical and Computer Engineering, AUB, 2004.;"Advisor: Dr. Karim Kabalan, Professor, Electrical and Computer Engineering--Member of Committee: Dr.
Dannan, Dana Nazir
core
FORMATION OF A METHOD FOR INCREASING THE RELIABILITY OF SPECIALIZED COMPUTERS
Background. Development of a methodological apparatus for constructing means to ensure the required level of probability of failure-free operation and survivability of self-healing specialized computers (SEVMs).
Aleksandr A. Pavlov +6 more
doaj +1 more source
Clinical pathway data engineering framework (CPDEF): a reproducible methodology for constructing machine learning-ready case-mix datasets from hospital information systems. [PDF]
Nugroho S, Ginardi RVH, Purnama IKE.
europepmc +1 more source
Vascular normalization confers an endothelial immune suppressive gene expression profile
We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Comparison of Capturing Children's Technology Use Using Wearable Camera and Fixed Room Video: Experimental Laboratory Study. [PDF]
Beynon A +8 more
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Finite-time and predefined-time dynamical systems for solving strongly pseudomonotone mixed equilibrium problems. [PDF]
Wen Q, Khan VK, Cai QB, Ahmad MK.
europepmc +1 more source

