Results 41 to 50 of about 1,186,675 (280)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
IEEE Photonics Journal, 2019 A tapered asymmetric directional coupler is considered as a promising structure for high tolerance and efficient on-chip mode (de)multiplexers. However, the optimum geometry parameters selection still remains empirical without specific numerical guidance.
Haowen Shu +5 more
doaj +1 more source
Photonics, 2021 This paper presents a Dual-sideband Optical Carrier Suppression (DSB-OCS) technique which is used to generate an optical millimeter-wave (mm-wave) signal in radio over fiber (RoF) systems.
Syamsuri Yaakob +5 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
IoT and Big Data Applications in Smart Cities: Recent Advances, Challenges, and Critical Issues
IEEE Access, 2021 The notion of smart cities has remained under evolution as its global implementations are challenged by numerous technological, economic, and governmental obstacles.
Marieh Talebkhah +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Hanle Detection for Optical Clocks
The Scientific World Journal, 2015 Considering the strong inhomogeneous spatial polarization and intensity distribution of spontaneous decay fluorescence due to the Hanle effect, we propose and demonstrate a universe Hanle detection configuration of electron-shelving method for optical ...
Xiaogang Zhang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sensors, 2019 The increase in drone misuse by civilian apart from military applications is alarming and need to be addressed. This drone is characterized as a low altitude, slow speed, and small radar cross-section (RCS) (LSS) target and is considered difficult to be ...
Surajo Alhaji Musa +4 more
doaj +1 more source