Results 151 to 160 of about 4,222,894 (339)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Algorithms for calculation damage processes

open access: yesFracture and Structural Integrity, 2019
The paper reviews the existing approaches to calculating the destruction of solids. The main attention is paid to algorithms using a unified approach to the calculation of deformation both for nondestructive and for the destroyed states of the material ...
Aleksandr Dmitrievich Nikitin   +3 more
doaj  

Prediction of SDG 6.2 Achievement in Indonesia Using Double Exponential Smoothing

open access: yesJurnal Sisfokom
This research aims to forecast Indonesia’s progress in achieving Sustainable Development Goal (SDG) 6.2, which targets 100% access to adequate sanitation and elimination of open defecation (OD) by 2030.
Nazwa Nabila   +2 more
doaj   +1 more source

Peer Review #2 of "Today’s computing challenges: opportunities for computer hardware design (v0.1)"

open access: gold, 2021
Woorham Bae   +99 more
openalex   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

An automated procedure for developing hybrid computer simulations of turbofan engines [PDF]

open access: yes
A systematic, computer-aided, self-documenting methodology for developing hybrid computer simulations of turbofan engines is presented. The methodology makes use of a host program that can run on a large digital computer and a machine-dependent target ...
Krosel, S. M., Szuch, J. R.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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