Results 151 to 160 of about 4,224,352 (310)

RNA nanotechnology for computer design and in vivo computation. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci, 2013
Qiu M   +6 more
europepmc   +1 more source

An application of interactive computer graphics technology to the design of dispersal mechanisms [PDF]

open access: yes, 1977
Interactive computer graphics technology is combined with a general purpose mechanisms computer code to study the operational behavior of three guided bomb dispersal mechanism designs.
Richter, B. J., Welch, B. H.
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Computational design of metalloproteases

open access: yes
Abstract Although significant progress has been made in creating de novo metalloenzymes that hydrolyze activated esters 1,2 , the energetically demanding cleavage of amide bonds has remained a major challenge for enzyme design: amide bonds are ...
Anqi Chen   +17 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Artwork Interactive Design System (AIDS) program description [PDF]

open access: yes
An artwork interactive design system is described which provides the microelectronic circuit designer/engineer a tool to perform circuit design, automatic layout modification, standard cell design, and artwork verification at a graphics computer terminal
Johnson, B. T., Taylor, J. F.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Algorithms for calculation damage processes

open access: yesFracture and Structural Integrity, 2019
The paper reviews the existing approaches to calculating the destruction of solids. The main attention is paid to algorithms using a unified approach to the calculation of deformation both for nondestructive and for the destroyed states of the material ...
Aleksandr Dmitrievich Nikitin   +3 more
doaj  

MMTransformer: a multivariate time-series resource forecasting model for multi-component applications

open access: yesScientific Reports
Efficient resource forecasting in multi-component application scenarios necessitates comprehensive consideration of inter-component dependencies and resource interaction characteristics.
Guangzhang Cui   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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