Results 181 to 190 of about 4,222,894 (339)

Fault Tolerant Design of Integrated Navigation Computer Based on SINS/CNS/GNSS [PDF]

, 2017
Ruimin Zhang, Xusheng Wang, Shigang Fan
openalex   +1 more source

Computer-aided design of bevel gear tooth surfaces [PDF]

This paper presents a computer-aided design procedure for generating bevel gears. The development is based on examining a perfectly plastic, cone-shaped gear blank rolling over a cutting tooth on a plane crown rack.
Coy, John J., Huston, Ronald L., Shuo, Hung Chang   +2 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The Teaching of Computer Assisted Sustainable Architectural Design [PDF]

, 1988
Raymond D. Reed
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Design of the Sequential Control System for Programmable Logic Controller based on Computer Aided Technology

, 2021
Yao Cun-zhi, Yingjie Wang
openalex   +1 more source

Computer code for intraply hybrid composite design [PDF]

A computer program is described for intraply hybrid composite design (INHYD). The program includes several composite micromechanics theories, intraply hybrid composite theories, and a hygrothermomechanical theory.
Chamis, C. C., Sinclair, J. H.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Exploring the Impact of Open Pedagogy on Minority Students' Motivation, Computational Thinking, and Perceived Learning in Interactive Computer Game Development. [PDF]

J Intell
Kuo YT, Kuo YC.
europepmc   +1 more source

Representations of time in computer interface design [PDF]

, 2007
Mitchell, Marilyn
core