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Design and computational flexibility
Digital Creativity, 2006Abstract This article discusses three levels of computer use—literacy, fluency and flexibility. Literacy is about the use of particular tools to satisfy well-defined tasks while fluency is a deeper form of knowledge that allows people to adapt to the uncertainties of computing and keep up with new, technological trends.
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Angewandte Chemie International Edition, 2013
Abstract Recent developments in computational chemistry and biology have come together in the “inside‐out” approach to enzyme engineering. Proteins have been designed to catalyze reactions not previously accelerated in nature. Some of these proteins fold and act as catalysts, but the success rate is still low.
Gert, Kiss +4 more
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Abstract Recent developments in computational chemistry and biology have come together in the “inside‐out” approach to enzyme engineering. Proteins have been designed to catalyze reactions not previously accelerated in nature. Some of these proteins fold and act as catalysts, but the success rate is still low.
Gert, Kiss +4 more
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Computational design of robots
ACM SIGGRAPH 2022 Courses, 2022James M. Bern +2 more
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Computational design of antibodies
Current Opinion in Structural Biology, 2018Antibody design aims to create new antibodies with biological activity that can be used in therapy and research. Traditional methods for antibody discovery, such as animal immunization and large-scale library screening, generate antibodies that bind to the target of interest, but do not necessarily have the desired functional effect.
Sharon, Fischman, Yanay, Ofran
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The computability of architectural design
Proceedings of the 5th Jerusalem Conference on Information Technology, 1990. 'Next Decade in Information Technology', 2002Two approaches, expressed in terms of mappings between design and computation, are explored with the intention of clarifying the relationship between the theories of design and computation. First, the relationship between models of the design process and computational search strategies is explored.
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Microprocessing and Microprogramming, 1990
Abstract In this paper the use of axiomatic computing models in designing is presented. The usefulness of the chosen approach is assessed by showing the specification and implementation of a symbolic multiplier. The formal definition of the multiplier of strings of digits is implemented in a fully-testable C-program, directly derived from the ...
Monica Alderighi +4 more
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Abstract In this paper the use of axiomatic computing models in designing is presented. The usefulness of the chosen approach is assessed by showing the specification and implementation of a symbolic multiplier. The formal definition of the multiplier of strings of digits is implemented in a fully-testable C-program, directly derived from the ...
Monica Alderighi +4 more
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2006
Most of the work of the computer architect today has to do with bridging the well-known gigantic gap between processor speed and memory access time. However, other significant challenges are looming on the horizon. For one thing, higher device density and smaller design rules are increasing the sensitivity of circuits to outside radiation events. Also,
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Most of the work of the computer architect today has to do with bridging the well-known gigantic gap between processor speed and memory access time. However, other significant challenges are looming on the horizon. For one thing, higher device density and smaller design rules are increasing the sensitivity of circuits to outside radiation events. Also,
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Computer-aided design for quantum computation
Proceedings of the International Conference on Computer-Aided Design, 2018Quantum computation is currently moving from an academic idea to a practical reality. The recent past has seen tremendous progress in the physical implementation of corresponding quantum computers - also involving big players such as IBM, Google, Intel, Rigetti, Microsoft, and Alibaba.
Robert Wille +2 more
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The History of Design in Computing
IEEE Annals of the History of Computing, 2018In this issue of the Annals, we are pleased to provide very different but equally unique contributions on the history of design in computing.
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Designing the human-computer interface
ACM SIGCSE Bulletin, 1982There is a growing awareness in the academic and industrial computing communities of the need to introduce human factors considerations into the design of computer systems. At the School of Information and Computer Science of the Georgia Institute of Technology, this need is being met through a well-funded graduate research program in the human factors
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