Results 271 to 280 of about 7,637,119 (365)

Integrated Computer Technologies in Mechanical Engineering - 2024 [PDF]

Lytvynov, Oleksii, Pavlikov, Volodymyr, Krytskyi, Dmytro   +2 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Retracted: Research on Load Balancing and Caching Strategy for Central Network

Journal of Electrical and Computer Engineering
Journal of Electrical and Computer Engineering
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Artificial intelligence for personalized management of vestibular schwannoma: a multidisciplinary clinical implementation study. [PDF]

JAMIA Open
Wijethilake N, Connor S, Oviedova A, Ivory M, Burger R, De Leon De Sagun J, Hitchings A, Abougamil A, Giannis T, Syrris C, Chia K, Al-Salihi O, Obholzer R, Jiang D, Maratos E, Barazi S, Thomas N, Vercauteren T, Shapey J.   +18 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Using explainable AI to align pre-university profiles with bachelor's degree success. [PDF]

Sci Rep
Rico-Juan JR, Pertegal-Felices ML, Jimeno-Morenilla A.   +2 more
europepmc   +1 more source

Overview of Computer-Aided Engineering of Batteries and Introduction to Multi-Scale, Multi-Dimensional Modeling of Li-Ion Batteries (Presentation)

, 2012
Ahmad Pesaran, G. H. Kim, Kandler Smith, S. Santhanagopalan, K. J. Lee   +4 more
openalex   +1 more source

Computer-aided Reverse Engineering for Rapid Replacement of Parts

, 2006
Dinesh Kumar Pal, L. S. Bhargava, B. Ravi, U. Chandrasekhar, U. Chandrasekhar   +4 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source