Results 31 to 40 of about 2,814,476 (338)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Are Wireless Sensors Feasible for Aircraft? [PDF]

open access: yes, 2009
Wireless communications is a preferred way of data transmission in many aerospace applications. Replacing some aircraft sensor wiring with wireless communications is a highly desirable but challenging transformation.
Demirkiran, Ilteris   +2 more
core   +1 more source

EngiNews, Spring 2021 [PDF]

open access: yes, 2021
In this issue: First graduating cohort in Computer Engineering • SHU Drone project with Prof.
School of Computer Science & Engineering,
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

EECE 7905/8905: Computational Science & Engineering III: Fluid-Structure Interaction (Syllabus) [PDF]

open access: yes, 2015
Course Description: Multiphysics simulations are useful for modeling the behavior of coupled systems governed by two or more physical laws and their interactions.
Balasubramanian, Madhusudhanan
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Graduate Curricula in Software Engineering and Software Assurance: Need and Recommendations [PDF]

open access: yes, 2010
In discussions about the development and use of computer systems and software products, the term “professional software engineer” is used repeatedly. In the last two decades there has been significant effort devoted to enhancing and advancing the state ...
Hilburn, T. B., Kornecki, Andrew J.
core   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Preface [PDF]

open access: yes, 2009
This special issue contains selected papers from the 18th European Symposium of Computer Aided Process Engineering (ESCAPE-18) which took place in Lyon, France, 1–4 June 2008.
Braunschweig, Bertrand, Joulia, Xavier
core   +1 more source

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