Results 51 to 60 of about 7,637,119 (365)

Using Experiential and Collaborative Learning to Promote Careers in Engineering [PDF]

open access: yes, 2019
This paper discusses the design of the Girls Accelerating and Learning STEM (G.A.L.S.) one-week residential summer camp designed to encourage young girls to pursue engineering careers. Specifically, the camp exposed participants to the fields of computer
Frizell, Sherri   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Mechatronics at the University of Twente [PDF]

open access: yes, 1997
This paper describes some of the mechatronics activities at the University of Twente. In 1989, the founding of the Mechatronics Research Center Twente started a cooperation of the departments of Electrical Engineering, Mechanical Engineering, Applied ...
Amerongen, Job van, Koster, Rien
core   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Computer Aided Engineering [PDF]

open access: yes, 2012
Current solutions in Computer Aided Process Planning (CAPP) can be time consuming, complex and costly to employ and still require the input of an experienced planner. Implementations can require a high degree of configuration, particularly when preexisting knowledge within the company needs to be incorporated.
Srichand Hinduja, Lin Li
openaire   +1 more source

Evaluating phase synchronization methods in fMRI: A comparison study and new approaches [PDF]

open access: yesNeuroImage, 2020
Hamed Honari   +12 more
semanticscholar   +1 more source

Computer program draws three-dimensional surfaces [PDF]

open access: yes, 1972
Computer plotting program PLOT 3D draws views of surface forms z = f(x,y). Surface thus defined by program may be drawn after arbitrary rotations. Program portrays behavior of various functions involving two variables in many engineering, physics, and ...
Canright, R. B., Jr., Swigert, P.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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