Results 111 to 120 of about 2,034,779 (346)

What do we learn from computer simulations of Bell experiments? [PDF]

, 2016
Marian Kupczyński
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Design of AR-based general computer technology experiment demonstration platform

Nonlinear Engineering
In order to improve the experimental demonstration effect of computer technology, this article combines virtual reality technology and intelligent reflective surface-assisted perception and communication technology to build a general computer experiment ...
Xu Fang
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Copolymer adsorption kinetics at a selective liquid-liquid interface: Scaling theory and computer experiment

, 2005
We consider the adsorption kinetics of a regular block-copolymer of total length $N$ and block size $M$ at a selective liquid-liquid interface in the limit of strong localization.
A Corsi, A Milchev, Balasz A. C., De Gennes P.-G., Garel T., Sommer J.-U., T. A Vilgis, V. G Rostiashvili   +7 more
core   +1 more source

COMBREX: COMputational BRidge to EXperiments [PDF]

Biochemical Society Transactions, 2011
COMBREX (computational bridges to experimentation) is a project to engage the biological community in providing better functional annotation of genomes. In essence, the project involves the generation by computational biologists of a database of predicted functions for genes in bacterial genomes.
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

OPVOEDKUNDIGE TEGNOLOGIE: REKENAARONDERSTEUNDE ONDERRIG IN DIE WEERMAG

Scientia Militaria, 2012
The South African Institute for Educational Research was requested by International Business Machines to conduct an experiment at the Department of Cataloguing and Codification of the South African Defence Force with computer-assisted instruction ...
D.L. Hattingh
doaj   +1 more source

Life sciences Spacelab Mission Development test 3 (SMD 3) data management report [PDF]

Development of a permanent data system for SMD tests was studied that would simulate all elements of the shuttle onboard, telemetry, and ground data systems that are involved with spacelab operations.
Moseley, E. C.
core   +1 more source

The Household Registration System: technology for the generation of computer software for longitudinal field experiments [PDF]

, 2001

openalex   +1 more source