Results 141 to 150 of about 2,034,779 (346)
Spacelab experiment computer study. Volume 2: Study elements and approach [PDF]
For abstract, see volume 1 N77 ...
Christy, J. O. +2 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Лесной журналThe consequences of operating road trains consisting of tractors with pole trailers in difficult road conditions have been described. Promising scientific directions have been presented contributing to increasing the efficiency of tractors with trailed ...
Valeryi I. Posmetyev +5 more
doaj
Reproducing quantum experiments on NISQ computers using high level quantum programming. [PDF]
, 2021 Duc Minh Tran +3 more
openalex
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Photogrammetric calibration of the NASA-Wallops Island image intensifier system [PDF]
An image intensifier was designed for use as one of the primary tracking systems for the barium cloud experiment at Wallops Island. Two computer programs, a definitive stellar camara calibration program and a geodetic stellar camara orientation program ...
Harp, B. F.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Modification of codes NUALGAM and BREMRAD. Volume 3: Statistical considerations of the Monte Carlo method [PDF]
The statistics are considered of the Monte Carlo method relative to the interpretation of the NUGAM2 and NUGAM3 computer code results.
Firstenberg, H.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source